Ruthenium(II) polypyridyl complexes and DNA--from structural probes to cellular imaging and therapeutics.
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The path for metal complexes to a DNA targetStructural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere SequenceMonitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopyTargeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(ii) polypyridyl complex†Electronic supplementary information (ESI) available: Experimental details, characterization of 2 and Fig. S1-S6. See DOI: 10.1039/c3sc5172A Family of Potent Ru(II) Photosensitizers with Enhanced DNA Intercalation: Bimodal Photokillers.Osmium(II) polypyridyl polyarginine conjugate as a probe for live cell imaging; a comparison of uptake, localization and cytotoxicity with its ruthenium(II) analogue.Heteroleptic mononuclear compounds of ruthenium(ii): synthesis, structural analyses, in vitro antitumor activity and in vivo toxicity on zebrafish embryos.Selective Luminescent Labeling of DNA and RNA Quadruplexes by π-Extended Ruthenium Light-Up Probes.Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands.Photoexpulsion of surface-grafted ruthenium complexes and subsequent release of cytotoxic cargos to cancer cells from mesoporous silica nanoparticles.Modifying charge and hydrophilicity of simple Ru(II) polypyridyl complexes radically alters biological activities: old complexes, surprising new tricks.Multifaceted interplay between lipophilicity, protein interaction and luminescence parameters of non-intercalative ruthenium(II) polypyridyl complexes controlling cellular imaging and cytotoxic properties.Phosphorescent imaging of living cells using a cyclometalated iridium (III) complexAcri-2,7-Py, a bright red-emitting DNA probe identified through screening of a distyryl dye library.From intercalation to groove binding: switching the DNA-binding mode of isostructural transition-metal complexes.Ultrafast photo-induced ligand solvolysis of cis-[Ru(bipyridine)2(nicotinamide)2](2+): experimental and theoretical insight into its photoactivation mechanism.Reversal of a Single Base-Pair Step Controls Guanine Photo-Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine ComplexSynthesis, relaxivity, and in vitro fluorescence imaging studies of a novel d-f heterometallic trinuclear complex as a potential bimodal imaging probe for MRI and optical imaging.Monitoring guanine photo-oxidation by enantiomerically resolved Ru(II) dipyridophenazine complexes using inosine-substituted oligonucleotides.New photosensitizers for photodynamic therapyInfluence of the Steric Bulk and Solvent on the Photoreactivity of Ruthenium Polypyridyl Complexes Coordinated to l-Proline.Duplex-selective ruthenium-based DNA intercalators.Mechanisms of small molecule-DNA interactions probed by single-molecule force spectroscopy.Ultrafast in cellulo photoinduced dynamics processes of the paradigm molecular light switch [Ru(bpy)2dppz](2.).Dual mode of cell death upon the photo-irradiation of a RuII polypyridyl complex in interphase or mitosis.Enabling the Triplet of Tetraphenylethene to Sensitize the Excited State of Europium(III) for Protein Detection and Time-Resolved Luminescence Imaging.Redox mediators in visible light photocatalysis: photocatalytic radical thiol-ene additions.Photoactivatable metal complexes: from theory to applications in biotechnology and medicine.Making a big thing of a small cell--recent advances in single cell analysis.When self-assembly meets biology: luminescent platinum complexes for imaging applications.RutheniumII complexes bearing fused polycyclic ligands: from fundamental aspects to potential applications.Ruthenium polypyridine complexes combined with oligonucleotides for bioanalysis: a review.Zinc complexes as fluorescent chemosensors for nucleic acids: new perspectives for a "boring" element.An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex.Ruthenium complexes as antimicrobial agents.Copper-Free Postsynthetic Labeling of Nucleic Acids by Means of Bioorthogonal Reactions.Optical imaging probes for biomolecules: an introductory perspective.Biological processing of dinuclear ruthenium complexes in eukaryotic cells.A survey of the mechanisms of action of anticancer transition metal complexes.Dinuclear ruthenium(ii) complexes containing one inert metal centre and one coordinatively-labile metal centre: syntheses and biological activities.
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Ruthenium(II) polypyridyl complexes and DNA--from structural probes to cellular imaging and therapeutics.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Ruthenium(II) polypyridyl comp ...... ular imaging and therapeutics.
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type
label
Ruthenium(II) polypyridyl comp ...... ular imaging and therapeutics.
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prefLabel
Ruthenium(II) polypyridyl comp ...... ular imaging and therapeutics.
@en
P2860
P356
P1476
Ruthenium(II) polypyridyl comp ...... lular imaging and therapeutics
@en
P2093
Jim A Thomas
Martin R Gill
P2860
P304
P356
10.1039/C2CS15299A
P577
2012-02-07T00:00:00Z