The N-terminal 45-kDa domain of Dna2 endonuclease/helicase targets the enzyme to secondary structure DNA
about
Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrityRad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.Borrowing nuclear DNA helicases to protect mitochondrial DNA.Yet another job for Dna2: Checkpoint activation.Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases.DNA2-An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein?GSK-3β Homolog Rim11 and the Histone Deacetylase Complex Ume6-Sin3-Rpd3 Are Involved in Replication Stress Response Caused by Defects in Dna2.hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability.
P2860
Q28118339-8A03805B-7F92-4D68-9A79-AAEA47ABEE0BQ33652233-FE35F571-9FA4-43BC-859D-ED15AC8CF16DQ35723527-0846A32B-0A7B-488C-996F-2E43C9408342Q35908832-30884408-32C9-413B-B674-B05E123D6F3BQ37270358-F32E8C0D-BD70-4387-A697-E329635094F2Q39441548-1515DBBE-BE52-4599-8A64-A9ACCDB438BDQ48197466-CB342A3C-BAF5-494D-946C-88D35F1188ECQ53775754-3E9135DE-670F-44EC-8D53-666B745E79B1
P2860
The N-terminal 45-kDa domain of Dna2 endonuclease/helicase targets the enzyme to secondary structure DNA
description
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name
The N-terminal 45-kDa domain o ...... yme to secondary structure DNA
@en
type
label
The N-terminal 45-kDa domain o ...... yme to secondary structure DNA
@en
prefLabel
The N-terminal 45-kDa domain o ...... yme to secondary structure DNA
@en
P2093
P2860
P356
P1476
The N-terminal 45-kDa domain o ...... yme to secondary structure DNA
@en
P2093
Chul-Hwan Lee
Do-Hyung Kim
Hyo-Jin Kang
Sung-Ho Bae
Yeon-Soo Seo
Young-Hoon Kang
P2860
P304
P356
10.1074/JBC.M112.418715
P407
P577
2013-01-22T00:00:00Z