Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro.
about
A CT promoter element binding protein: definition of a double-strand and a novel single-strand DNA binding motifDirect evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcriptionTherapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesHeterogeneous nuclear ribonucleoprotein K is a transcription factorStroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteasesDNA and the chromosome - varied targets for chemotherapyTriplex-induced recombination and repair in the pyrimidine motif.Kinetic resolution of bimolecular hybridization versus intramolecular folding in nucleic acids by surface plasmon resonance: application to G-quadruplex/duplex competition in human c-myc promoter.The hidden side of unstable DNA repeats: Mutagenesis at a distanceStructure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit PromoterThe bi-loop, a new general four-stranded DNA motifDNA tetraplex formation in the control region of c-mycTriplex hydration: nanosecond molecular dynamics simulation of the solvated triplex formed by mixed sequences.A fiber optic biosensor for fluorimetric detection of triple-helical DNA.Proton exchange and local stability in a DNA triple helix containing a G.TA triadSynthesis and triplex forming properties of pyrimidine derivative containing extended functionality.Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway.Control of gene expression by triple helix-forming oligonucleotides. The antigene strategy.Induction of duplex to G-quadruplex transition in the c-myc promoter region by a small molecule.Characterization of a triplex DNA-binding protein encoded by an alternative reading frame of loricrin.Triple helices formed at oligopyrimidine*oligopurine sequences with base pair inversions: effect of a triplex-specific ligand on stability and selectivity.Enhanced cellular uptake of a triplex-forming oligonucleotide by nanoparticle formation in the presence of polypropylenimine dendrimersExploring the reasons for the large density of triplex-forming oligonucleotide target sequences in the human regulatory regionsSequence-specific DNA purification by triplex affinity capture.Specific inhibition of transcription by triple helix-forming oligonucleotidesMolecular models for intrastrand DNA G-quadruplexes.Improved bioactivity of G-rich triplex-forming oligonucleotides containing modified guanine bases.Triple-helix formation by alpha oligodeoxynucleotides and alpha oligodeoxynucleotide-intercalator conjugates.Triplex formation inhibits HER-2/neu transcription in vitroTargeting and processing of site-specific DNA interstrand crosslinks.Structure of the biologically relevant G-quadruplex in the c-MYC promoter.A molecular anchor for stabilizing triple-helical DNA.Suicidal nucleotide sequences for DNA polymerization.Recognition of Single-Stranded Nucleic Acids by Triplex Formation: The Binding of Pyrimidine-Rich Sequences.Proton NMR studies of 5'-d-(TC)(3) (CT)(3) (AG)(3)-3'--a paperclip triplex: the structural relevance of turns.Internal dynamics in a DNA triple helix probed by (1)H-(15)N-NMR spectroscopy.Triplex technology in studies of DNA damage, DNA repair, and mutagenesisTriplexator: detecting nucleic acid triple helices in genomic and transcriptomic data.Triple helical DNA in a duplex context and base pair opening.Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates.
P2860
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P2860
Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Site-specific oligonucleotide ...... the human c-myc gene in vitro.
@en
type
label
Site-specific oligonucleotide ...... the human c-myc gene in vitro.
@en
prefLabel
Site-specific oligonucleotide ...... the human c-myc gene in vitro.
@en
P2093
P356
P1433
P1476
Site-specific oligonucleotide ...... the human c-myc gene in vitro.
@en
P2093
P304
P356
10.1126/SCIENCE.3293213
P407
P577
1988-07-01T00:00:00Z