A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells
about
Towards vast libraries of scaffold-diverse, conformationally constrained oligomers.Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targetsA Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis.Development of a large peptoid-DOTA combinatorial library.Chromodomain Ligand Optimization via Target-Class Directed Combinatorial RepurposingDiscovery of an Inhibitor of the Proteasome Subunit Rpn11.The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle ProgressionCharacterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation.Establishment of a suite of assays that support the discovery of proteasome stimulators.An overview of peptide and peptoid foldamers in medicinal chemistry.Targeting proteasome ubiquitin receptor Rpn13 in multiple myeloma.Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma.Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.One-Bead-Two-Compound Thioether Bridged Macrocyclic γ-AApeptide Screening Library against EphA2.Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism.Ubiquitin Receptor RPN13 Mediates the Inhibitory Interaction of Diphenyldihaloketones CLEFMA and EF24 With the 26S Proteasome
P2860
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P2860
A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A reversible and highly select ...... oxic to multiple myeloma cells
@en
type
label
A reversible and highly select ...... oxic to multiple myeloma cells
@en
prefLabel
A reversible and highly select ...... oxic to multiple myeloma cells
@en
P2860
P356
P1476
A reversible and highly select ...... oxic to multiple myeloma cells
@en
P2093
Darci J Trader
Thomas Kodadek
P2860
P304
P356
10.1021/JACS.5B02069
P407
P577
2015-05-08T00:00:00Z