Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity.

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Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand Role and inhibition of GLI1 protein in cancer.Role of GLI Transcription Factors in Pathogenesis and Their Potential as New Therapeutic Targets

P2860

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P2860

Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity.

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http://www.wikidata.org/entity/Q38740268

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Solasonine, A Natural Glycoalk ...... ated Transcriptional Activity.

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Solasonine, A Natural Glycoalk ...... ated Transcriptional Activity.

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Solasonine, A Natural Glycoalk ...... ated Transcriptional Activity.

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P1476

Solasonine, A Natural Glycoalk ...... iated Transcriptional Activity

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P2093

Jun Yang

http://www.w3.org/2001/XMLSchema#string

Wenfu Tan

http://www.w3.org/2001/XMLSchema#string

Wenjing Huang

http://www.w3.org/2001/XMLSchema#string

P2860

Small molecule modulation of Smoothened activity

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

Smoothened variants explain the majority of drug resistance in basal cell carcinoma

Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells

Hedgehog: functions and mechanisms

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.

Developmental toxicology of solamargine and solasonine glycoalkaloids in frog embryos.

Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth.

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.

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scholarly article

P356

10.3390/MOLECULES21101364

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English

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2016-10-14T00:00:00Z

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27754442

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6274431

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Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity.

about

P2860

P2860

Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P31

P356

P407

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P31

P356

P407

P433

P478

P577

P698

P932