The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells.

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In This Issue: Protein Structure, Cellular Metabolism, and Genetics in Immunity.An immortalized steroidogenic goat granulosa cell line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis.

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The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells.

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The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells.

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The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells.

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P1476

The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells

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Ana Sofia Martins

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Bruno Miguel Neves

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Inês Alves

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Luisa Helguero

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Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

Plasma cell differentiation requires the transcription factor XBP-1

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing

Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival

Emerging functions of the unfolded protein response in immunity

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457-476

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scholarly article

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10.3109/08830185.2015.1110151

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Maria Rosario M Domingues

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2016-04-27T00:00:00Z

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27119724

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The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells.

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P2860

P2860

The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells.

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P1476

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