Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability.
about
THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.Protein kinase D regulates positive selection of CD4(+) thymocytes through phosphorylation of SHP-1.THEMIS: Two Models, Different Thresholds.Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms.Grb2-Mediated Recruitment of USP9X to LAT Enhances Themis Stability following Thymic Selection.Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function.Themis2 lowers the threshold for B cell activation during positive selection.SHP1-ing thymic selection.
P2860
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P2860
Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Themis1 enhances T cell recept ...... 1 activity and Grb2 stability.
@en
Themis1 enhances T cell recept ...... 1 activity and Grb2 stability.
@nl
type
label
Themis1 enhances T cell recept ...... 1 activity and Grb2 stability.
@en
Themis1 enhances T cell recept ...... 1 activity and Grb2 stability.
@nl
prefLabel
Themis1 enhances T cell recept ...... 1 activity and Grb2 stability.
@en
Themis1 enhances T cell recept ...... 1 activity and Grb2 stability.
@nl
P2093
P2860
P1433
P1476
Themis1 enhances T cell recept ...... v1 activity and Grb2 stability
@en
P2093
Anne Garreau
Ekaterina Zvezdova
Gaëtan Blaize
Judith Mikolajczak
Julien Familiades
Jérémy Argenty
Lise Rigal
Marlène Marcellin
P2860
P356
10.1126/SCISIGNAL.AAD1576
P577
2016-05-17T00:00:00Z