If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?

If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?

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ITC recommendations for transporter kinetic parameter estimation and translational modeling of transport-mediated PK and DDIs in humansFitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithmPgp-mediated interaction between (R)-[11C]verapamil and tariquidar at the human blood-brain barrier: a comparison with rat dataTransport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.A novel application of t-statistics to objectively assess the quality of IC50 fits for P-glycoprotein and other transportersVariability in P-glycoprotein inhibitory potency (IC₅₀) using various in vitro experimental systems: implications for universal digoxin drug-drug interaction risk assessment decision criteria.Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomographyComputational approaches to analyse and predict small molecule transport and distribution at cellular and subcellular levelsIn vitro methods to support transporter evaluation in drug discovery and development.Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter.The importance of villous physiology and morphology in mechanistic physiologically-based pharmacokinetic models.
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If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?

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http://www.wikidata.org/entity/Q39778869
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If the KI is defined by the fr ...... ce 1 confluent cell monolayer?
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If the KI is defined by the fr ...... ce 1 confluent cell monolayer?
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type
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If the KI is defined by the fr ...... ce 1 confluent cell monolayer?
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If the KI is defined by the fr ...... ce 1 confluent cell monolayer?
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If the KI is defined by the fr ...... ce 1 confluent cell monolayer?
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If the KI is defined by the fr ...... ce 1 confluent cell monolayer?
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P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
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P1433
P1476
If the KI is defined by the fr ...... ce 1 confluent cell monolayer?
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921