about
Involvement of the Rho/Rac family member RhoG in caveolar endocytosisRegulatory and signaling properties of the Vav familyA mouse model for Costello syndrome reveals an Ang II-mediated hypertensive conditionRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses3D structure of Syk kinase determined by single-particle electron microscopyGTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoVav family exchange factors: an integrated regulatory and functional viewThe Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loopsReduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren SyndromeThe 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism.Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle.Structural basis for the signaling specificity of RhoG and Rac1 GTPasesHuman Proteinpedia enables sharing of human protein dataTyrosine phosphorylation of the vav proto-oncogene product links FcepsilonRI to the Rac1-JNK pathwayThe C-terminal SH3 domain contributes to the intramolecular inhibition of Vav family proteins.Role of Src homology domain binding in signaling complexes assembled by the murid γ-herpesvirus M2 protein.Structural determinants for the biological activity of Vav proteins.Global conformational rearrangements during the activation of the GDP/GTP exchange factor Vav3.Conformational rearrangements upon Syk auto-phosphorylation.Vav3-deficient mice exhibit a transient delay in cerebellar developmentConstitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome.The disease-linked Glu-26-Lys mutant version of Coronin 1A exhibits pleiotropic and pathway-specific signaling defects.S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells.The Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assemblyThe use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasisThe Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells.T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis.VAV3 mediates resistance to breast cancer endocrine therapy.Vav1 and Rac control chemokine-promoted T lymphocyte adhesion mediated by the integrin alpha4beta1Vav3 is involved in GABAergic axon guidance events important for the proper function of brainstem neurons controlling cardiovascular, respiratory, and renal parameters.Vav proteins, adaptors and cell signaling.Transcriptional factor aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogenePhylogenetic conservation of the regulatory and functional properties of the Vav oncoprotein family.K-RasV14I recapitulates Noonan syndrome in mice.Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells.Activation of Vav by the gammaherpesvirus M2 protein contributes to the establishment of viral latency in B lymphocytesUnderstanding Rho/Rac biology in T-cells using animal models.A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton.New avenue to inhibit Ras signaling.Loss of Vav2 proto-oncogene causes tachycardia and cardiovascular disease in mice.
P50
Q24544120-A2534CA2-6F63-407F-A99B-B814985D79A1Q24554307-ADA52913-0D18-4184-BB53-D261F47C606DQ24655745-10DBD7CE-1AC5-496E-BEDF-A6B97618D7B2Q24681250-36D7D7C0-C5B6-4B3B-8751-FAC8FEF80845Q24683676-729CD1B5-B8DF-499C-96C9-83DDAE8000B6Q24685451-F45C3B07-82D0-4C2C-B4FE-E6B63120FCAAQ27026905-0C565AA6-DE00-4358-88DD-ECBD6D8F77E7Q27317069-9F7D6D47-913C-4BCE-822C-C786CC111CC8Q27335096-E11A5E96-9829-4807-95B2-83EE5B7D49B1Q27933023-F4210C15-4ED5-45B1-AE4A-21A9746850F5Q27936916-502B5109-44B9-4B1E-9ACC-326E88753E69Q28178941-2D452AA5-A395-4591-A17F-E1298259E3A1Q28267923-2983D0D0-32ED-4D53-9332-ED9C4F733153Q28646531-6BC4DDAD-523E-4B79-B47D-D705085804EEQ30009435-E385E924-9599-4597-B728-BD004ACA0FE6Q30009958-EBCD7039-C126-4B18-ACC7-A901F257F2FFQ30165211-E01A174B-8616-4DC9-8A17-1F72D322412CQ30475942-DCE8F0E2-A9E7-481C-96D5-A332B1D2E7EDQ30490298-5042762F-18FA-4CC9-B334-4B535918A34DQ30493610-843C350E-7673-4A3B-9F66-74FED838F86FQ30499131-68FD1BF8-0795-43DD-AA09-F473A7DF448DQ30664640-007FC8AD-6CE1-4761-B87D-73766F46FADDQ32060838-30086F40-D73F-4526-860B-2ED9B2720352Q33321224-F50590D1-EE4E-4FAF-8DF9-6D3B3592E7A9Q33518516-18AD402B-59F0-43CF-A5B0-72216B202FE4Q33559599-77C943F0-F887-43AE-846D-4164FF0D88A8Q33660194-E94146E8-861B-4C50-81DD-340C88929310Q33827037-B574C063-3523-4BA0-99BC-26235C31911BQ33877050-40EB7A01-CDDD-40CF-89E9-755D83D47737Q34361011-71FD3E6C-211B-445D-BFB3-4C70F72B5D86Q34405552-44B46990-FEC1-49F7-BCEA-2A00CADEB3A5Q34509506-9717D55F-BA85-4CEA-A2B0-AB7E5AD19411Q34565554-44DF083A-0443-4833-9251-45EDC7B3F201Q34581270-3E197AF0-693D-449B-A112-326EC487ABAFQ34592816-3BFCA3D6-802F-4EB0-B32E-387B770D7126Q34651249-B5B7889F-5CF3-4CC0-8CC3-48D860EE60C6Q34732889-6B82D66F-09C5-4331-B0DE-56741C1C5B59Q35029238-693FE641-82C8-45C1-B50A-FDBDDB412DA4Q35530757-785895A6-EB93-4FF1-B02D-CDD56A0E9EC2Q35650885-EE392984-98CF-4187-868B-33E9AEDC347E
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Xosé R Bustelo
@nl
Xosé R Bustelo
@sl
Xosé R. Bustelo
@en
Xosé R. Bustelo
@es
type
label
Xosé R Bustelo
@nl
Xosé R Bustelo
@sl
Xosé R. Bustelo
@en
Xosé R. Bustelo
@es
altLabel
Xose R. Bustelo
@en
prefLabel
Xosé R Bustelo
@nl
Xosé R Bustelo
@sl
Xosé R. Bustelo
@en
Xosé R. Bustelo
@es
P1053
A-9526-2010
P106
P1153
7004908425
P21
P31
P3829
P496
0000-0001-9398-6072