about
PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migrationVav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformationOligomerization of DH domain is essential for Dbl-induced transformationSmall GTPase RhoG is a key regulator for neurite outgrowth in PC12 cellsVav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrinsVav family proteins couple to diverse cell surface receptorsVav-2 controls NFAT-dependent transcription in B- but not T-lymphocytesVav2 is required for cell spreadingThe B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survivalVav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activationGranulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogensSignalling pathways induced by protease-activated receptors and integrins in T cellsVav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancerRho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseVav family exchange factors: an integrated regulatory and functional viewPTP-PEST couples membrane protrusion and tail retraction via VAV2 and p190RhoGAP.The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loopsNovel recognition mode between Vav and Grb2 SH3 domainsTwo Closely Spaced Tyrosines Regulate NFAT Signaling in B Cells via Syk Association with VavDifferential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domainCD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating CellsStructural basis for a novel interaction between TXNIP and Vav2Structural basis for the signaling specificity of RhoG and Rac1 GTPasesAML1 interconnected pathways of leukemogenesisUnifying concepts in CD28, ICOS and CTLA4 co-receptor signallingHyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growthVav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyteVav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathwaysHematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytesLeukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytesAssociation of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathwayCD28 and CTLA-4 coreceptor expression and signal transductionMechanisms of type-I- and type-II-interferon-mediated signallingRegulation of cell adhesion by protein-tyrosine phosphatases. I. Cell-matrix adhesionCharacterization of the biochemical and transforming properties of the neuroepithelial transforming protein 1PAK1 negatively regulates the activity of the Rho exchange factor NET1Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesisVav GEFs are required for beta2 integrin-dependent functions of neutrophils.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Regulatory and signaling properties of the Vav family
@ast
Regulatory and signaling properties of the Vav family
@en
Regulatory and signaling properties of the Vav family
@nl
type
label
Regulatory and signaling properties of the Vav family
@ast
Regulatory and signaling properties of the Vav family
@en
Regulatory and signaling properties of the Vav family
@nl
prefLabel
Regulatory and signaling properties of the Vav family
@ast
Regulatory and signaling properties of the Vav family
@en
Regulatory and signaling properties of the Vav family
@nl
P2860
P1476
Regulatory and signaling properties of the Vav family
@en
P2093
X R Bustelo
P2860
P304
P356
10.1128/MCB.20.5.1461-1477.2000
P407
P577
2000-03-01T00:00:00Z