Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors.
about
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesRSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activationTwo p90 ribosomal S6 kinase isoforms are involved in the regulation of mitotic and meiotic arrest in Artemia.Low expression of RSK4 predicts poor prognosis in patients with colorectal cancer.MicroRNAs Regulate Key Effector Pathways of SenescenceInactivation of X-linked tumor suppressor genes in human cancer.Aberrant methylation of the X-linked ribosomal S6 kinase RPS6KA6 (RSK4) in endometrial cancers.The possible role of ribosomal protein S6 kinase 4 in the senescence of endothelial progenitor cells in diabetes mellitusBasic anatomy and tumor biology of the RPS6KA6 gene that encodes the p90 ribosomal S6 kinase-4.RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer.Down-Regulation of Ribosomal S6 kinase RPS6KA6 in Acute Myeloid Leukemia Patients.Ribosomal s6 protein kinase 4: a prognostic factor for renal cell carcinomap16(Ink4a) overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors.Ribosomal S6 kinase 4 (RSK4) expression in ovarian tumors and its regulation by antineoplastic drugs in ovarian cancer cell lines.Ribosomal S6 kinase (RSK) modulators: a patent review.Frequent epigenetic inactivation of RSK4 by promoter methylation in cancerous and non-cancerous tissues of breast cancer.RSK4 inhibition results in bypass of stress-induced and oncogene-induced senescence.Paving the way for targeting RSK in cancer.
P2860
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P2860
Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Regulation of replicative and ...... own-regulated in human tumors.
@en
Regulation of replicative and ...... own-regulated in human tumors.
@nl
type
label
Regulation of replicative and ...... own-regulated in human tumors.
@en
Regulation of replicative and ...... own-regulated in human tumors.
@nl
prefLabel
Regulation of replicative and ...... own-regulated in human tumors.
@en
Regulation of replicative and ...... own-regulated in human tumors.
@nl
P2093
P50
P1476
Regulation of replicative and ...... down-regulated in human tumors
@en
P2093
Berta Pons
Elisabet Argelaguet
Inés de Torres
Laura Coch
Laura López-Vicente
Matilde Lleonart
P304
P356
10.1158/1078-0432.CCR-08-3159
P407
P577
2009-07-07T00:00:00Z