TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis.
about
Cancer stem cells and immunoresistance: clinical implications and solutionsThe Janus Face of Death Receptor Signaling during Tumor ImmunoeditingER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosisTargeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisonsBid regulates the pathogenesis of neurotropic reovirus.X-linked ectodermal dysplasia receptor is downregulated in breast cancer via promoter methylation.Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice.TRAIL receptor signaling regulation of chemosensitivity in vivo but not in vitroGenome-wide association study identifies multiple risk loci for renal cell carcinoma.Inhibition of the intrinsic but not the extrinsic apoptosis pathway accelerates and drives MYC-driven tumorigenesis towards acute myeloid leukemia.The TRAIL of oncogenes to apoptosis.Oncogenic stress sensed by the immune system: role of natural killer cell receptorsTargeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis.Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs.A New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase.Peroxiredoxin 6 interferes with TRAIL-induced death-inducing signaling complex formation by binding to death effector domain caspase.TNF superfamily protein-protein interactions: feasibility of small- molecule modulationEnhancing apoptosis in TRAIL-resistant cancer cells using fundamental response rulesThe relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo.Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis.Regulation in the targeting of TRAIL receptor 1 to cell surface via GODZ for TRAIL sensitivity in tumor cellsDeficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis.Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling.TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them.Breast implant-associated ALK-negative anaplastic large cell lymphoma: a case report and discussion of possible pathogenesisAgonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal ToxicityLife and death by death receptors.Metastasis suppressor function of tumor necrosis factor-related apoptosis-inducing ligand-R in mice: implications for TRAIL-based therapy in humans?The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway.Following TRAIL's path in the immune system.Emerging apoptosis agonists for bladder cancer.TRAIL receptor signaling and therapeutics.Fucosylation and gastrointestinal cancer.Targeting the extrinsic apoptosis signaling pathway for cancer therapy.Deconstructing p53 transcriptional networks in tumor suppression.TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment.Resistance to TRAIL and how to surmount it.TNF related apoptosis-inducing ligand and its receptors in ocular tumors.Regulation of the human TRAIL gene.Cancer stem cell immunology: key to understanding tumorigenesis and tumor immune escape?
P2860
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P2860
TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
TRAIL-R deficiency in mice pro ...... nflammation and tumorigenesis.
@en
type
label
TRAIL-R deficiency in mice pro ...... nflammation and tumorigenesis.
@en
prefLabel
TRAIL-R deficiency in mice pro ...... nflammation and tumorigenesis.
@en
P2093
P2860
P356
P1476
TRAIL-R deficiency in mice pro ...... nflammation and tumorigenesis.
@en
P2093
Andres J P Klein-Szanto
Niklas Finnberg
Wafik S El-Deiry
P2860
P304
P356
10.1172/JCI29900
P407
P577
2008-01-01T00:00:00Z