Rex transregulation of human T-cell leukemia virus type II gene expression.
about
HTLV-1 Rex is required for viral spread and persistence in vivo but is dispensable for cellular immortalization in vitro.Phosphorylation of two serine residues regulates human T-cell leukemia virus type 2 Rex function.Human T-cell leukemia virus type 1 expressing nonoverlapping tax and rex genes replicates and immortalizes primary human T lymphocytes but fails to replicate and persist in vivo.Tax and overlapping rex sequences do not confer the distinct transformation tropisms of human T-cell leukemia virus types 1 and 2Mechanism of action of regulatory proteins encoded by complex retrovirusesPolypyrimidine tract-binding protein and heterogeneous nuclear ribonucleoprotein A1 bind to human T-cell leukemia virus type 2 RNA regulatory elements.Complete nucleotide sequence of the new simian T-lymphotropic virus, STLV-PH969 from a Hamadryas baboon, and unusual features of its long terminal repeatThe human T-cell leukemia virus Rex proteinHuman T-cell leukemia virus type II Rex binding and activity require an intact splice donor site and a specific RNA secondary structureFunctional domain structure of human T-cell leukemia virus type 2 rex.Human T-cell leukemia virus type 2 Rex carboxy terminus is an inhibitory/stability domain that regulates Rex functional activity and viral replication.Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulator.Human T-cell leukemia virus type 2 Rex inhibits pre-mRNA splicing in vitro at an early stage of spliceosome formation.Inhibition of human T-cell leukemia virus type 2 Rex function by truncated forms of Rex encoded in alternatively spliced mRNAs.Specific binding of the human T-cell leukemia virus type I Rex protein to a short RNA sequence located within the Rex-response element.Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance.Functional analysis of human T-cell leukemia virus type I rex-response element: direct RNA binding of Rex protein correlates with in vivo activity.
P2860
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P2860
Rex transregulation of human T-cell leukemia virus type II gene expression.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Rex transregulation of human T-cell leukemia virus type II gene expression.
@en
type
label
Rex transregulation of human T-cell leukemia virus type II gene expression.
@en
prefLabel
Rex transregulation of human T-cell leukemia virus type II gene expression.
@en
P2093
P2860
P1433
P1476
Rex transregulation of human T-cell leukemia virus type II gene expression
@en
P2093
P2860
P304
P407
P577
1991-01-01T00:00:00Z