Inhibition of hepatitis C virus IRES-mediated translation by small RNAs analogous to stem-loop structures of the 5'-untranslated region.
about
A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIIdA peptide derived from RNA recognition motif 2 of human la protein binds to hepatitis C virus internal ribosome entry site, prevents ribosomal assembly, and inhibits internal initiation of translation.Searching for IRESInhibition of hepatitis C virus by an M1GS ribozyme derived from the catalytic RNA subunit of Escherichia coli RNase PRe-analysis of cryoEM data on HCV IRES bound to 40S subunit of human ribosome integrated with recent structural information suggests new contact regions between ribosomal proteins and HCV RNAInhibition of hepatitis C virus replication by single-stranded RNA structural mimics.Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.Two internal ribosome entry sites mediate the translation of p53 isoforms.Secondary Structural Elements of the HCV X-region Involved in Viral ReplicationReversible induction of translational isoforms of p53 in glucose deprivation.Targeting ribosome assembly on the HCV RNA using a small RNA moleculeHepatitis C viral protein translation: mechanisms and implications in developing antivirals.La protein binding at the GCAC site near the initiator AUG facilitates the ribosomal assembly on the hepatitis C virus RNA to influence internal ribosome entry site-mediated translation.The beta hairpin structure within ribosomal protein S5 mediates interplay between domains II and IV and regulates HCV IRES function.Hepatitis C virus core protein acts as a trans-modulating factor on internal translation initiation of the viral RNA.
P2860
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P2860
Inhibition of hepatitis C virus IRES-mediated translation by small RNAs analogous to stem-loop structures of the 5'-untranslated region.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Inhibition of hepatitis C viru ...... of the 5'-untranslated region.
@en
type
label
Inhibition of hepatitis C viru ...... of the 5'-untranslated region.
@en
prefLabel
Inhibition of hepatitis C viru ...... of the 5'-untranslated region.
@en
P2860
P356
P1476
Inhibition of hepatitis C viru ...... of the 5'-untranslated region
@en
P2093
Saumitra Das
P2860
P304
P356
10.1093/NAR/GKH328
P577
2004-03-12T00:00:00Z