Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.
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Alzheimer's disease as homeostatic responses to age-related myelin breakdownMolecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4The intracellular domain of ErbB4 induces differentiation of mammary epithelial cellsThe ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperonePhosphorylation of ErbB4 on tyrosine 1056 is critical for ErbB4 coupling to inhibition of colony formation by human mammary cell linesPTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid raftsAmyloid precursor protein modulates beta-catenin degradationProteolytic Processing of ErbB4 in Breast CancerThe Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragmentsProcessing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcriptionEndoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-proteinThe E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradationErbB4 expression in neural progenitor cells (ST14A) is necessary to mediate neuregulin-1beta1-induced migrationPresenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brainCell death or survival promoted by alternative isoforms of ErbB4A new functional screening system for identification of regulators for the generation of amyloid beta-protein.Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition state inhibitor of "gamma-secretase".Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes.The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation.HER4 D-box sequences regulate mitotic progression and degradation of the nuclear HER4 cleavage product s80HER4.Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathwayActivity-dependent transcription regulation of PSD-95 by neuregulin-1 and Eos.Presenilin-1 processing of ErbB4 in fetal type II cells is necessary for control of fetal lung maturation.Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancerChronic administration of anti-stroke herbal medicine TongLuoJiuNao reduces amyloidogenic processing of amyloid precursor protein in a mouse model of Alzheimer's diseaseSignalling shortcuts: cell-surface receptors in the nucleus?A nuclear variant of ErbB3 receptor tyrosine kinase regulates ezrin distribution and Schwann cell myelination.Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease.HER4 in breast cancer: comparison of antibodies against intra- and extra-cellular domains of HER4A dynamic relationship between intracellular and extracellular pools of Abeta.Physiologic and pathologic events mediated by intramembranous and juxtamembranous proteolysis.Expression of ErbB4 in the neurons of Alzheimer's disease brain and APP/PS1 mice, a model of Alzheimer's diseaseThe EGF receptor family--multiple roles in proliferation, differentiation, and neoplasia with an emphasis on HER4Estrogen-induced upregulation of Sftpb requires transcriptional control of neuregulin receptor ErbB4 in mouse lung type II epithelial cells.An Alzheimer's disease hypothesis based on transcriptional dysregulation.Neuregulin receptor ErbB4 functions as a transcriptional cofactor for the expression of surfactant protein B in the fetal lung.ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response.Dysregulated ErbB4 Splicing in Schizophrenia: Selective Effects on Parvalbumin ExpressionAn NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
P2860
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P2860
Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.
@en
type
label
Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.
@en
prefLabel
Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.
@en
P2093
P356
P1476
Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4
@en
P2093
Hahn-Jun Lee
Joanne S Lee
Lori B Bennett
Tae-Wan Kim
Yang Z Huang
P304
P356
10.1074/JBC.M110371200
P407
P577
2001-12-10T00:00:00Z