An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors.
about
Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zetaSolution structure of midkine, a new heparin-binding growth factorA high throughput messenger RNA differential display screen identifies discrete domains of gene expression and novel patterning processes along the developing neural tube.Midkine and cytoplasmic maturation of mammalian oocytes in the context of ovarian follicle physiologyStructure and function of midkine as the basis of its pharmacological effectsThe Mice Drawer System (MDS) experiment and the space endurance record-breaking miceHB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix.Neointima formation in a restenosis model is suppressed in midkine-deficient miceMidkine, heparin-binding growth factor, blocks kainic acid-induced seizure and neuronal cell death in mouse hippocampusFell-Muir Lecture: Heparan sulphate and the art of cell regulation: a polymer chain conducts the protein orchestra.Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescenceStructure and phylogenetic analysis of an endogenous retrovirus inserted into the human growth factor gene pleiotrophin.Behavioral and neuroanatomical abnormalities in pleiotrophin knockout mice.Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase CThe role of pleiotrophin and beta-catenin in fetal lung development.A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζExpression analysis of macrodactyly identifies pleiotrophin upregulation.The Drosophila midkine/pleiotrophin homologues Miple1 and Miple2 affect adult lifespan but are dispensable for alk signaling during embryonic gut formation.Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and arteminPleiotrophin as a central nervous system neuromodulator, evidences from the hippocampus.Effects of pleiotrophin overexpression on mouse skeletal muscles in normal loading and in actual and simulated microgravity.Pleiotrophin over-expression provides trophic support to dopaminergic neurons in parkinsonian ratsPleiotrophin commits human bone marrow mesenchymal stromal cells towards hypertrophy during chondrogenesisMidkine: a promising molecule for drug development to treat diseases of the central nervous systemDominant negative pleiotrophin induces tetraploidy and aneuploidy in U87MG human glioblastoma cells.Pleiotrophin expression during odontogenesisPleiotrophin transforms NIH 3T3 cells and induces tumors in nude mice.N-syndecan deficiency impairs neural migration in brain.Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases.A dominant-negative pleiotrophin mutant introduced by homologous recombination leads to germ-cell apoptosis in male mice.Loss of receptor protein tyrosine phosphatase β/ζ (RPTPβ/ζ) promotes prostate cancer metastasisExpression of P30, a protein with adhesive properties, in Schwann cells and neurons of the developing and regenerating peripheral nerve.Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis.Midkine promoter-based conditionally replicative adenovirus therapy for midkine-expressing human pancreatic cancer.Human trophoblast and choriocarcinoma expression of the growth factor pleiotrophin attributable to germ-line insertion of an endogenous retrovirus.Enhanced antitumorigenic effects in glioblastoma on double targeting of pleiotrophin and its receptor ALK.VEGF and pleiotrophin modulate the immune profile of breast cancer.Structural and functional characterization of full-length heparin-binding growth associated molecule.Pleiotrophin regulates lung epithelial cell proliferation and differentiation during fetal lung development via beta-catenin and Dlk1.The midkine family of growth factors: diverse roles in nervous system formation and maintenance.
P2860
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P2860
An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
An 18-kd heparin-binding prote ...... rom fibroblast growth factors.
@en
type
label
An 18-kd heparin-binding prote ...... rom fibroblast growth factors.
@en
prefLabel
An 18-kd heparin-binding prote ...... rom fibroblast growth factors.
@en
P2860
P1433
P1476
An 18-kd heparin-binding prote ...... rom fibroblast growth factors.
@en
P2860
P304
P407
P577
1989-10-01T00:00:00Z