How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication.
about
CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome.Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination.Mrc1/Claspin: a new role for regulation of origin firing.Mechanisms of DNA replication termination.From structure to mechanism-understanding initiation of DNA replication.Regulation and Modulation of Human DNA Polymerase δ Activity and Function.Nuclear DNA Replication in Trypanosomatids: There Are No Easy Methods for Solving Difficult Problems.Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks.Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates.Arranging eukaryotic nuclear DNA polymerases for replication: Specific interactions with accessory proteins arrange Pols α, δ, and ϵ in the replisome for leading-strand and lagging-strand DNA replication.Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin.Initiation of Drosophila chorion gene amplification requires Claspin and mus101, whereas Claspin, but not mus101, plays a major role during elongation.Nucleosomes influence multiple steps during replication initiationChromatin replication: TRANSmitting the histone code.The DNA Pol ϵ stimulatory activity of Mrc1 is modulated by phosphorylation.A Redox Role for the [4Fe4S] Cluster of Yeast DNA Polymerase δ.Redox-sensitive alteration of replisome architecture safeguards genome integrity.Noise in the Machine: Alternative Pathway Sampling is the Rule During DNA Replication.Dependency of Heterochromatin Domains on Replication Factors.Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress.Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome.Building up and breaking down: mechanisms controlling recombination during replication.Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts.The need to regulate replication fork speed.The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism.Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae.DNA replication through a chromatin environment.Translesion and Repair DNA Polymerases: Diverse Structure and Mechanism.The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy.The INO80 remodeller in transcription, replication and repair.Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning.Thinking Outside the Cell: Replicating Replication In Vitro.The Initial Response of a Eukaryotic Replisome to DNA Damage.Histone H2A-H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatinDNA polymerase ε-dependent modulation of the pausing property of the CMG helicase at the barrierThe replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesionRecent advances in understanding DNA replication: cell type-specific adaptation of the DNA replication programp15PAF binding to PCNA modulates the DNA sliding surface
P2860
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P2860
How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication.
@en
type
label
How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication.
@en
prefLabel
How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication.
@en
P2093
P2860
P1433
P1476
How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication
@en
P2093
Agnieska Janska
Anne Early
Joseph T P Yeeles
P2860
P304
P356
10.1016/J.MOLCEL.2016.11.017
P577
2016-12-15T00:00:00Z