A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.
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Structure of the TRPA1 ion channel suggests regulatory mechanismsHow the TRPA1 receptor transmits painful stimuli: Inner workings revealed by electron cryomicroscopyTRP Channels in Respiratory Pathophysiology: the Role of Oxidative, Chemical Irritant and Temperature StimuliDeciphering Subtype-Selective Modulations in TRPA1 Biosensor ChannelsMechanical allodyniaTRPA1 as a drug target--promise and challengesThe perception and endogenous modulation of painTRPA1 channels in the vasculatureA Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating DomainSensory detection and responses to toxic gases: mechanisms, health effects, and countermeasures.Modulation of the Activities of Neuronal Ion Channels by Fatty Acid-Derived Pro-ResolventsNociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain PathologiesMechanically Activated Ion ChannelsTransient receptor potential channels as therapeutic targetsTransient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases.TRPA1 mediates mechanical sensitization in nociceptors during inflammationMethylglyoxal evokes pain by stimulating TRPA1TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed ratsContribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel.TRPA1 contributes to cold hypersensitivityPiezo2 is required for Merkel-cell mechanotransductionTmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent PainStructural basis of TRPA1 inhibition by HC-030031 utilizing species-specific differences.Sensitization of the trigeminovascular system following environmental irritant exposureCellular and Molecular Mechanisms of PainThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsTRPA1 agonists evoke coughing in guinea pig and human volunteersRetinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivityExuberant sprouting of sensory and sympathetic nerve fibers in nonhealed bone fractures and the generation and maintenance of chronic skeletal pain.TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice.Transient receptor potential (TRP) channels: a clinical perspectiveTransient receptor potential (TRP) channels in the airway: role in airway disease.Tumor tissue-derived formaldehyde and acidic microenvironment synergistically induce bone cancer pain.TRPA1 expression and its functional activation in rodent cortex.A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation.Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in miceBehavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats.4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo.Transient receptor potential channel A1 and noxious cold responses in rat cutaneous nociceptorsDeletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression.
P2860
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P2860
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.
@en
type
label
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.
@en
prefLabel
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.
@en
P2093
P2860
P356
P1433
P1476
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition
@en
P2093
Andrea M Peier
Ardem Patapoutian
Matt Petrus
Michael Bandell
Nicholas Olney
Truc Huynh
P2860
P2888
P356
10.1186/1744-8069-3-40
P577
2007-12-17T00:00:00Z
P5875
P6179
1033311980