Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells
about
Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cellsKnow the enemy as well as the weapons in hand: the aberrant death pathways and therapeutic agents in chronic lymphocytic leukemiaInhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXATargeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cellsThe carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1MiR-200c regulates Noxa expression and sensitivity to proteasomal inhibitors.The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells.Regulation of the DNA damage response by ubiquitin conjugation.Higher expression of SIRT1 induced resistance of esophageal squamous cell carcinoma cells to cisplatin.Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytesSall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicinThe proteasome inhibitor carfilzomib functions independently of p53 to induce cytotoxicity and an atypical NF-κB response in chronic lymphocytic leukemia cells.A novel dithiocarbamate analogue with potentially decreased ALDH inhibition has copper-dependent proteasome-inhibitory and apoptosis-inducing activity in human breast cancer cellsCharacterization of a Dual CDC7/CDK9 Inhibitor in Multiple Myeloma Cellular ModelsAberrantly activated anti-apoptotic signalling mechanisms in chronic lymphocytic leukaemia cells: clues to the identification of novel therapeutic targets.Design of novel BH3 mimetics for the treatment of chronic lymphocytic leukemia.Apoptosis inducers in chronic lymphocytic leukemia.The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistanceShort Chemical Ischemia Triggers Phosphorylation of eIF2α and Death of SH-SY5Y Cells but not Proteasome Stress and Heat Shock Protein Response in both SH-SY5Y and T98G Cells.Noxa and cancer therapy: Tuning up the mitochondrial death machinery in response to chemotherapy.ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia.Discrepant NOXA (PMAIP1) transcript and NOXA protein levels: a potential Achilles' heel in mantle cell lymphoma.Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage.NOXA, a sensor of proteasome integrity, is degraded by 26S proteasomes by an ubiquitin-independent pathway that is blocked by MCL-1Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer.Proteasome inhibitor carfilzomib complements ibrutinib's action in chronic lymphocytic leukemia.γ-Secretase inhibitor I induces apoptosis in chronic lymphocytic leukemia cells by proteasome inhibition, endoplasmic reticulum stress increase and notch down-regulation.Targeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death.Regulation of stressed-induced cell death by the Bcl-2 family of apoptotic proteins.Proteasome Stress Triggers Death of SH-SY5Y and T98G Cells via Different Cellular Mechanisms.Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.Histone Deacetylase Inhibitor Enhances the Efficacy of MEK Inhibitor through NOXA-Mediated MCL1 Degradation in Triple-Negative and Inflammatory Breast Cancer.Bortezomib stabilizes NOXA and triggers ROS-associated apoptosis in medulloblastoma.Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA
P2860
Q24298561-B614E050-616F-44B3-8525-766EA1418D7DQ26781895-BF9C5246-A795-4B2B-8DC7-B4194B28289FQ28830560-988146AB-4644-4F6E-B65A-349537E3B905Q33710037-D5C70FFC-FB36-44B1-8A24-88F28011A101Q33793022-EE40E5C3-DDB0-404C-86CF-98753C90E45EQ34277271-C4F5B98D-F2F0-4E49-810C-E7162CAEEB1DQ34557856-6908E30A-BB68-44AE-A0E3-BA3174E90B51Q34912378-12AE8B47-6002-4911-A2B1-410AEA6CAE58Q35161624-0B2482F2-312C-439A-BE1A-DAF6167F0064Q35568388-886A7338-26A5-425E-9258-5023C5EC4CA7Q35823218-16823DC4-9AFA-4E1E-8270-E4B66A9350A7Q36293819-F4FF57B4-06B4-4481-AD88-7D7AF8A416DFQ36815262-93347DAD-24A9-4B12-BEA4-DBB3C10AEE84Q36900376-70D4F19A-0F2D-4108-9204-FCBB8067076DQ37226506-5FC27C7A-6431-49BD-B22F-CF5D5A8B145DQ37866334-CD32FC2E-CA78-4079-92A8-465293FCB951Q37997623-13D602FD-7431-498A-9CA6-5BCDEA1FE9A0Q38187815-DC8DED8E-AA86-4E7D-89A6-3CA18C652C53Q38347433-F318EEA1-DE7F-4DA0-830D-0BF62559B4B8Q38818265-44C1F967-C17C-4E0A-B9DA-B3CD55B5994BQ38866647-EF4DCC17-274E-4365-815C-E44D847722EFQ38891225-4AF9C0E1-C6B1-42D9-A888-DD792726409DQ39031250-ED0C5BB2-55C9-447E-9324-8D31C6ACBDAFQ40552928-D08AAE19-4127-4780-8E1B-B558F8910A68Q41851050-08FBA682-0DFC-4B85-B0A9-99DCF7A57726Q42003270-577B4A70-E92E-424F-9109-0BEAADE2B880Q43096794-A53BB15A-9346-4A8C-84AB-C8C2ABC77EBCQ46067297-7BA4E0AC-7D63-42E4-8619-E7A16F2BAE90Q46294171-BA909EC7-DC20-4ECD-8A72-5C2F7CB408B4Q47373163-1D58A9F9-1B5B-4D66-BA05-8BE61B7B6E21Q50880972-B0EDD06E-867C-4FBC-99C6-2572E42F052BQ50911306-BF5CFE38-FFA2-4B26-AAFB-CA8778C5113CQ51023485-E27258E6-FE3B-40AF-ABA4-C5396449EC97Q53243559-E42715BA-EE0C-4A59-9374-8F3F77EA30CBQ58765200-94F5582C-A3C5-49C9-8171-1E0A8A2D69B3
P2860
Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Role of NOXA and its ubiquitin ...... nic lymphocytic leukemia cells
@en
type
label
Role of NOXA and its ubiquitin ...... nic lymphocytic leukemia cells
@en
prefLabel
Role of NOXA and its ubiquitin ...... nic lymphocytic leukemia cells
@en
P2093
P2860
P921
P1433
P1476
Role of NOXA and its ubiquitin ...... nic lymphocytic leukemia cells
@en
P2093
Aneela Majid
David Dinsdale
Eric Eldering
Gerald M Cohen
Maria Baou
Martin J S Dyer
Meike Vogler
Michael Butterworth
Renata Walewska
Susan L Kohlhaas
P2860
P304
P356
10.3324/HAEMATOL.2010.022368
P577
2010-04-07T00:00:00Z