Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
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Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cellsCD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell linesCD300f associates with IL-4 receptor α and amplifies IL-4-induced immune cell responsesEnhanced efferocytosis by dendritic cells underlies memory T-cell expansion and susceptibility to autoimmune disease in CD300f-deficient miceCutting edge: mouse CD300f (CMRF-35-like molecule-1) recognizes outer membrane-exposed phosphatidylserine and can promote phagocytosisDisrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment.CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 productionThe CD300 molecules: an emerging family of regulators of the immune system.CD300b regulates the phagocytosis of apoptotic cells via phosphatidylserine recognition.The Receptor CMRF35-Like Molecule-1 (CLM-1) Enhances the Production of LPS-Induced Pro-Inflammatory Mediators during Microglial Activation.CD300f immunoreceptor contributes to peripheral nerve regeneration by the modulation of macrophage inflammatory phenotype.Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor.Apoptotic cell clearance of Leishmania major-infected neutrophils by dendritic cells inhibits CD8⁺ T-cell priming in vitro by Mer tyrosine kinase-dependent signalingInterleukin-33 requires CMRF35-like molecule-1 expression for induction of myeloid cell activation.Synthetic peptides containing ITIM-like domains block expression of inflammatory mediators and migration/invasion of cancer cells through activation of SHP-1 and PI3K.Synthetic peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling through activation of SHP and/or PI3K.Synthetic peptides containing ITIM-like sequences of IREM-1 inhibit BAFF-mediated regulation of interleukin-8 expression and phagocytosis through SHP-1 and/or PI3K.Immune receptor expressed on myeloid cells 1 (IREM-1) inhibits B cell activation factor (BAFF)-mediated inflammatory regulation of THP-1 cells through modulation of the activities of extracellular regulated kinase (ERK).Monocytes Phenotype and Cytokine Production in Human Immunodeficiency Virus-1 Infected Patients Receiving a Modified Vaccinia Ankara-Based HIV-1 Vaccine: Relationship to CD300 Molecules Expression.CSSI workshop in Brazil highlights "Stress Responses in the Nervous System" in relation to neurodegenerative diseases and neuroprotection.Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multiple SclerosisOverexpression of the immunoreceptor CD300f has a neuroprotective role in a model of acute brain injury.CD300 family receptors regulate eosinophil survival, chemotaxis, and effector functions.Rare heterozygous truncating variations and risk of autism spectrum disorder: Whole-exome sequencing of a multiplex family and follow-up study in a Japanese population.Specific lipid recognition is a general feature of CD300 and TREM molecules.CMRF35-like molecule 1 (CLM-1) regulates eosinophil homeostasis by suppressing cellular chemotaxis.Tropism for tuft cells determines immune promotion of norovirus pathogenesis.A key requirement for CD300f in innate immune responses of eosinophils in colitis.Inhibitory receptor expression on neonatal immune cells
P2860
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P2860
Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
@en
type
label
Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
@en
prefLabel
Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
@en
P2093
P2860
P50
P356
P1476
Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
@en
P2093
Hilary Clark
Hongkang Xi
Karim Y Helmy
Kenneth J Katschke
Menno van Lookeren Campagne
Noelyn Kljavin
Paige A Wark
Theresa Shek
P2860
P356
10.1084/JEM.20091508
P407
P577
2009-12-28T00:00:00Z