IREM-1 is a novel inhibitory receptor expressed by myeloid cells
about
CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell linesCD84 negatively regulates IgE high-affinity receptor signaling in human mast cellsAncient divergence of a complex family of immune-type receptor genes.Expression, crystallization and X-ray data collection from microcrystals of the extracellular domain of the human inhibitory receptor expressed on myeloid cells IREM-1.Functional analysis of activating receptor LMIR4 as a counterpart of inhibitory receptor LMIR3.Sequence specificity of SHP-1 and SHP-2 Src homology 2 domains. Critical roles of residues beyond the pY+3 position.The CD300 molecules: an emerging family of regulators of the immune system.The Receptor CMRF35-Like Molecule-1 (CLM-1) Enhances the Production of LPS-Induced Pro-Inflammatory Mediators during Microglial Activation.CD300f immunoreceptor contributes to peripheral nerve regeneration by the modulation of macrophage inflammatory phenotype.The expression and function of human CD300 receptors on blood circulating mononuclear cells are distinct in neonates and adultsImmune inhibitory receptors: essential regulators of phagocyte function.Antibody therapy for acute myeloid leukaemia.Regulation of neutrophil functions through inhibitory receptors: an emerging paradigm in health and disease.Interleukin-33 requires CMRF35-like molecule-1 expression for induction of myeloid cell activation.SHPS-1 and a synthetic peptide representing its ITIM inhibit the MyD88, but not TRIF, pathway of TLR signaling through activation of SHP and PI3K in THP-1 cells.Synthetic peptides containing ITIM-like domains block expression of inflammatory mediators and migration/invasion of cancer cells through activation of SHP-1 and PI3K.Synthetic peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling through activation of SHP and/or PI3K.Synthetic peptides containing ITIM-like sequences of IREM-1 inhibit BAFF-mediated regulation of interleukin-8 expression and phagocytosis through SHP-1 and/or PI3K.BAFF and APRIL induce inflammatory activation of THP-1 cells through interaction with their conventional receptors and activation of MAPK and NF-κB.Stimulation of FasL induces production of proinflammatory mediators through activation of mitogen-activated protein kinases and nuclear factor-κB in THP-1 cells.Characterization of leukocyte mono-immunoglobulin-like receptor 7 (LMIR7)/CLM-3 as an activating receptor: its similarities to and differences from LMIR4/CLM-5.Immune receptor expressed on myeloid cells 1 (IREM-1) inhibits B cell activation factor (BAFF)-mediated inflammatory regulation of THP-1 cells through modulation of the activities of extracellular regulated kinase (ERK).Human CD300C delivers an Fc receptor-γ-dependent activating signal in mast cells and monocytes and differs from CD300A in ligand recognition.CD300 heterocomplexes, a new and family-restricted mechanism for myeloid cell signaling regulation.Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors.Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multiple SclerosisOverexpression of the immunoreceptor CD300f has a neuroprotective role in a model of acute brain injury.Monoclonal antibodies against IREM-1: potential for targeted therapy of AML.The CD300e molecule in mice is an immune-activating receptor.
P2860
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P2860
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@ast
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@en
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@nl
type
label
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@ast
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@en
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@nl
prefLabel
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@ast
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@en
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@nl
P2093
P2860
P50
P3181
P356
P1476
IREM-1 is a novel inhibitory receptor expressed by myeloid cells
@en
P2093
Friederike Kitzig
Helena Aguilar
Tamara Brckalo
P2860
P304
P3181
P356
10.1002/EJI.200425433
P407
P577
2004-12-01T00:00:00Z