Serine threonine kinase Pim-3 regulates STAT3 pathway to inhibit proliferation of human liver cancers.

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Pim-3 as a potential predictor of chemoradiotherapy resistance in locally advanced rectal cancer patients.

P2860

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Serine threonine kinase Pim-3 regulates STAT3 pathway to inhibit proliferation of human liver cancers.

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http://www.wikidata.org/entity/Q41971269

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2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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Serine threonine kinase Pim-3 ...... ration of human liver cancers.

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type

Item

label

Serine threonine kinase Pim-3 ...... ration of human liver cancers.

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Serine threonine kinase Pim-3 ...... ration of human liver cancers.

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P1476

Serine threonine kinase Pim-3 ...... ration of human liver cancers.

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P2093

Hui Zhao

http://www.w3.org/2001/XMLSchema#string

Jianqiang Wang

http://www.w3.org/2001/XMLSchema#string

Lijun Lao

http://www.w3.org/2001/XMLSchema#string

Yuan Huang

http://www.w3.org/2001/XMLSchema#string

P2860

Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis

Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

Global cancer statistics, 2002

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death

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348-355

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scholarly article

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2014-02-15T00:00:00Z

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24600488

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3931587

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Serine threonine kinase Pim-3 regulates STAT3 pathway to inhibit proliferation of human liver cancers.

about

P2860

P2860

Serine threonine kinase Pim-3 regulates STAT3 pathway to inhibit proliferation of human liver cancers.

description

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P1476

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P2860

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P433

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P932

P1433

P1476

P2093

P2860

P304

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P433

P478

P577

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P932