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Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient MiceRegulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathwayAquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiationDynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growthCCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformationsAquaporin 3, a glycerol and water transporter, is regulated by p73 of the p53 family.Aquaporin-3 in keratinocytes and skin: its role and interaction with phospholipase D2.Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.Cerebral cavernous malformations arise independent of the heart of glass receptor.AngII induces transient phospholipase D activity in the H295R glomerulosa cell model.Elevated K(+) induces myristoylated alanine-rich C-kinase substrate phosphorylation and phospholipase D activation in glomerulosa cells.Modulation of phospholipase D-mediated phosphatidylglycerol formation by differentiating agents in primary mouse epidermal keratinocytes.Phospholipase d signaling and extracellular signal-regulated kinase-1 and -2 phosphorylation (activation) are required for maximal phorbol ester-induced transglutaminase activity, a marker of keratinocyte differentiation.A MicroRNA302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability.Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformationsEnrichment of regulatory CD4(+)CD25(+) T cells by inhibition of phospholipase D signalingA potential role for the phospholipase D2-aquaporin-3 signaling module in early keratinocyte differentiation: production of a phosphatidylglycerol signaling lipidDistinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformationTargeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Xiangjian Zheng
@ast
Xiangjian Zheng
@en
Xiangjian Zheng
@es
Xiangjian Zheng
@nl
Xiangjian Zheng
@sl
type
label
Xiangjian Zheng
@ast
Xiangjian Zheng
@en
Xiangjian Zheng
@es
Xiangjian Zheng
@nl
Xiangjian Zheng
@sl
prefLabel
Xiangjian Zheng
@ast
Xiangjian Zheng
@en
Xiangjian Zheng
@es
Xiangjian Zheng
@nl
Xiangjian Zheng
@sl
P108
P106
P31
P496
0000-0001-6277-5168