about
CIN85 regulates dopamine receptor endocytosis and governs behaviour in miceMTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairmentsNeurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humansA broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviourRestless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalonDoes enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse linesLarge-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous systemInterplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant MicePleiotropic functions for transcription factor zscan10.A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner.Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function.Requirement of the RNA-editing enzyme ADAR2 for normal physiology in miceMouse phenotyping.Innovations in phenotyping of mouse models in the German Mouse Clinic.Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory studyRapamycin extends murine lifespan but has limited effects on aging.A robust and reliable non-invasive test for stress responsivity in mice.MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adultsPleiotropic effects in Eya3 knockout mice.Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellumVoluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests.Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients.Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors.cGMP-dependent protein kinase I, the circadian clock, sleep and learning.The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.Systemic first-line phenotyping.Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.Analysis of locomotor behavior in the German Mouse Clinic.Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.MiR-34a deficiency accelerates medulloblastoma formation in vivo.MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation.Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 I27N mutant mice.
P50
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P50
description
hulumtuese
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հետազոտող
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M Hölter
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Sabine M. Hölter-Koch
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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Sabine M. Hölter
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P1053
N-5868-2014
P106
P1153
6701524578
P21
P2798
P31
P3829
P3835
sabine-m-hlter
P496
0000-0003-4878-5241