KvLQT1 modulates the distribution and biophysical properties of HERG. A novel alpha-subunit interaction between delayed rectifier currents.
about
HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cellsDominant-negative inhibition of M-like potassium conductances in hair cells of the mouse inner earCellular and molecular mechanisms of autosomal dominant form of progressive hearing loss, DFNA2.Emerging concepts in the pharmacogenomics of arrhythmias: ion channel trafficking.Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines.Electrophysiological and functional effects of the KCNQ channel blocker XE991 on murine portal vein smooth muscle cells.A dual mechanism for I(Ks) current reduction by the pathogenic mutation KCNQ1-S277L.KCNE Regulation of K(+) Channel Trafficking - a Sisyphean Task?Interactions between hERG and KCNQ1 α-subunits are mediated by their COOH termini and modulated by cAMP.Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome.Molecular Basis of Functional Myocardial Potassium Channel Diversity.KCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing?Heterodimerization between the lutropin and follitropin receptors is associated with an attenuation of hormone-dependent signaling.[Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes.Arrhythmogenic KCNE gene variants: current knowledge and future challenges.Interaction between the cardiac rapidly (IKr) and slowly (IKs) activating delayed rectifier potassium channels revealed by low K+-induced hERG endocytic degradation.Transmural gradients in ion channel and auxiliary subunit expression.Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator.Muscarinic modulation of erg potassium current.Trafficking-competent KCNQ1 variably influences the function of HERG long QT alleles.Wiring the developing heart: a serious matter for adulthood.Kir2.1-Nav1.5 Channel Complexes Are Differently Regulated than Kir2.1 and Nav1.5 Channels Alone.Kv4.3 Modulates the Distribution of hERG.Ion Channel Trafficking: Control of Ion Channel Density as a Target for Arrhythmias?A hERG mutation E1039X produced a synergistic lesion on IKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations.The interaction between delayed rectifier channel alpha-subunits does not involve hetero-tetramer formation.Cardiac Kir2.1 and NaV1.5 Channels Traffic Together to the Sarcolemma to Control Excitability.
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P2860
KvLQT1 modulates the distribution and biophysical properties of HERG. A novel alpha-subunit interaction between delayed rectifier currents.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
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name
KvLQT1 modulates the distribut ...... en delayed rectifier currents.
@en
KvLQT1 modulates the distribut ...... en delayed rectifier currents.
@nl
type
label
KvLQT1 modulates the distribut ...... en delayed rectifier currents.
@en
KvLQT1 modulates the distribut ...... en delayed rectifier currents.
@nl
prefLabel
KvLQT1 modulates the distribut ...... en delayed rectifier currents.
@en
KvLQT1 modulates the distribut ...... en delayed rectifier currents.
@nl
P2093
P2860
P356
P1476
KvLQT1 modulates the distribut ...... en delayed rectifier currents.
@en
P2093
Aida M Marmabachi
Joachim R Ehrlich
Manjula Weerapura
Marc Pourrier
Nathalie Ethier
Terence E Hébert
P2860
P304
P356
10.1074/JBC.M309087200
P407
P577
2003-10-29T00:00:00Z