Generation of a parainfluenza virus type 1 vaccine candidate by replacing the HN and F glycoproteins of the live-attenuated PIV3 cp45 vaccine virus with their PIV1 counterparts.

Generation of a parainfluenza virus type 1 vaccine candidate by replacing the HN and F glycoproteins of the live-attenuated PIV3 cp45 vaccine virus with their PIV1 counterparts.

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http://www.wikidata.org/entity/Q45746790
Replacement of the ectodomains of the hemagglutinin-neuraminidase and fusion glycoproteins of recombinant parainfluenza virus type 3 (PIV3) with their counterparts from PIV2 yields attenuated PIV2 vaccine candidatesReplacement of the F and G proteins of respiratory syncytial virus (RSV) subgroup A with those of subgroup B generates chimeric live attenuated RSV subgroup B vaccine candidates.Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates.Human parainfluenza virus type 3 (PIV3) expressing the hemagglutinin protein of measles virus provides a potential method for immunization against measles virus and PIV3 in early infancy.Recombinant human parainfluenza virus type 2 with mutations in V that permit cellular interferon signaling are not attenuated in non-human primates.Progress in the development of human parainfluenza virus vaccinesLive-attenuated virus vaccines for respiratory syncytial and parainfluenza viruses: applications of reverse genetics.Nonsegmented negative-strand viruses as vaccine vectors.Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes.Attenuated Human Parainfluenza Virus Type 1 (HPIV1) Expressing the Fusion Glycoprotein of Human Respiratory Syncytial Virus (RSV) as a Bivalent HPIV1/RSV Vaccine.Recombinant human parainfluenza virus type 2 vaccine candidates containing a 3' genomic promoter mutation and L polymerase mutations are attenuated and protective in non-human primates.Role of interferon in the replication of human parainfluenza virus type 1 wild type and mutant viruses in human ciliated airway epithelium.Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primates.Codon substitution mutations at two positions in the L polymerase protein of human parainfluenza virus type 1 yield viruses with a spectrum of attenuation in vivo and increased phenotypic stability in vitro.Generation of recombinant human parainfluenza virus type 1 vaccine candidates by importation of temperature-sensitive and attenuating mutations from heterologous paramyxoviruses.Inhibition of primary clinical isolates of human parainfluenza virus by DAS181 in cell culture and in a cotton rat model.
P2860

Generation of a parainfluenza virus type 1 vaccine candidate by replacing the HN and F glycoproteins of the live-attenuated PIV3 cp45 vaccine virus with their PIV1 counterparts.

Item
http://www.wikidata.org/entity/Q45746790
description
1999 nî lūn-bûn
@nan
1999年の論文
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1999年学术文章
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1999年学术文章
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1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Generation of a parainfluenza ...... with their PIV1 counterparts.
@en
Generation of a parainfluenza ...... with their PIV1 counterparts.
@nl
type
label
Generation of a parainfluenza ...... with their PIV1 counterparts.
@en
Generation of a parainfluenza ...... with their PIV1 counterparts.
@nl
prefLabel
Generation of a parainfluenza ...... with their PIV1 counterparts.
@en
Generation of a parainfluenza ...... with their PIV1 counterparts.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
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P1433
P1476
Generation of a parainfluenza ...... with their PIV1 counterparts.
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P2093
P304
P31
P356
10.1016/S0264-410X(99)00227-3
P407
P433
P478
P577
P698
P921