Neuregulin growth factors and their ErbB receptors form a potential signaling network for schwannoma tumorigenesis.
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Epidermal growth factor signaling in transformed cellsp75NTR is highly expressed in vestibular schwannomas and promotes cell survival by activating nuclear transcription factor κB.Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2.Erlotinib for progressive vestibular schwannoma in neurofibromatosis 2 patients.Microarray analysis of gene expression in vestibular schwannomas reveals SPP1/MET signaling pathway and androgen receptor deregulation.Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasmsTreatment of vestibular schwannoma cells with ErbB inhibitorsErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma.The ErbB inhibitors trastuzumab and erlotinib inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary studyA genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin.Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent mannerClassic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.Malignant peripheral nerve sheath tumor invasion requires aberrantly expressed EGF receptors and is variably enhanced by multiple EGF family ligands.Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesisERBB4 confers metastatic capacity in Ewing sarcomaEmerging therapeutic targets in schwannomas and other merlin-deficient tumors.Links between Schwann cells and melanocytes in development and disease.Schwannomas and their pathogenesis.Epiregulin: roles in normal physiology and cancerNeuregulin-ERBB signaling in the nervous system and neuropsychiatric diseasesThe coexistence of peripheral nerve sheath tumors and vitiligo: more than coincidence?Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas.
P2860
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P2860
Neuregulin growth factors and their ErbB receptors form a potential signaling network for schwannoma tumorigenesis.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
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name
Neuregulin growth factors and ...... for schwannoma tumorigenesis.
@en
Neuregulin growth factors and ...... for schwannoma tumorigenesis.
@nl
type
label
Neuregulin growth factors and ...... for schwannoma tumorigenesis.
@en
Neuregulin growth factors and ...... for schwannoma tumorigenesis.
@nl
prefLabel
Neuregulin growth factors and ...... for schwannoma tumorigenesis.
@en
Neuregulin growth factors and ...... for schwannoma tumorigenesis.
@nl
P1476
Neuregulin growth factors and ...... for schwannoma tumorigenesis.
@en
P2093
Abhik Ray Chaudhury
Stephanie J Byer
P304
P356
10.1097/01.JNEN.0000199575.93794.2F
P577
2006-02-01T00:00:00Z