SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy.
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External and internal triggers of cell death in yeastSirt1 and the MitochondriaThe associations between Parkinson's disease and cancer: the plot thickensΑlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's DiseaseNovel subcellular localization for α-synuclein: possible functional consequencesThe benefits of humanized yeast models to study Parkinson's diseaseEssential genetic interactors of SIR2 required for spatial sequestration and asymmetrical inheritance of protein aggregatesPhosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's diseaseTranscriptional and epigenetic regulation of autophagy in agingATP13A2 and Alpha-synuclein: a Metal Taste in AutophagyNuclear DNA damage signalling to mitochondria in ageingLoss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons.Yeast replicative aging: a paradigm for defining conserved longevity interventions.Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons.One single method to produce native and Tat-fused recombinant human α-synuclein in Escherichia coli.Complex network-driven view of genomic mechanisms underlying Parkinson's disease: analyses in dorsal motor vagal nucleus, locus coeruleus, and substantia nigraThe yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availabilityα-Synuclein and mitochondria: partners in crime?Sirtuins in neurodegenerative diseases: an update on potential mechanisms.Mitochondrion-mediated cell death: dissecting yeast apoptosis for a better understanding of neurodegeneration.Harnessing the power of yeast to unravel the molecular basis of neurodegeneration.Sirtuins' modulation of autophagy.SIRT1 in neurodevelopment and brain senescence.A mitocentric view of Parkinson's disease.Pharmacogenetics of drug response in Parkinson's disease.Dynamic droplets: the role of cytoplasmic inclusions in stress, function, and disease.Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins.Sirtuins and proteolytic systems: implications for pathogenesis of synucleinopathies.Longevity pathways and maintenance of the proteome: the role of autophagy and mitophagy during yeast ageing.Sirtuins as modifiers of Parkinson's disease pathology.(Poly)phenols protect from α-synuclein toxicity by reducing oxidative stress and promoting autophagy.Exploring the power of yeast to model aging and age-related neurodegenerative disorders.Dynamin 1-like-dependent mitochondrial fission initiates overactive mitophagy in the hepatotoxicity of cadmium.From the baker to the bedside: yeast models of Parkinson's disease.Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1-3Quality control of mitochondria during aging: is there a good and a bad side of mitochondrial dynamics?Human Thyroid Cancer-1 (TC-1) is a vertebrate specific oncogenic protein that protects against copper and pro-apoptotic genes in yeast.Yeast models for amyloid disease.Does eating less make you live longer and better? An update on calorie restriction.Melatonin improves survival and respiratory activity of yeast cells challenged by alpha-synuclein and menadione.
P2860
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P2860
SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
SNCA (α-synuclein)-induced tox ...... n 2 (Sir2)-mediated mitophagy.
@en
SNCA
@nl
type
label
SNCA (α-synuclein)-induced tox ...... n 2 (Sir2)-mediated mitophagy.
@en
SNCA
@nl
prefLabel
SNCA (α-synuclein)-induced tox ...... n 2 (Sir2)-mediated mitophagy.
@en
SNCA
@nl
P2093
P2860
P50
P356
P1433
P1476
SNCA (α-synuclein)-induced tox ...... n 2 (Sir2)-mediated mitophagy.
@en
P2093
Joris Winderickx
Márcio Rodrigues
Tiago F Outeiro
Vanessa Franssens
P2860
P304
P356
10.4161/AUTO.21275
P50
P577
2012-08-23T00:00:00Z