about
JNK1 phosphorylates SIRT1 and promotes its enzymatic activityCalorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylaseBinding of manumycin A inhibits IkappaB kinase beta activityCalorie restriction induces mitochondrial biogenesis and bioenergetic efficiencyRapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous miceImpact of caloric restriction on health and survival in rhesus monkeys from the NIA studyEvaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous miceNutrient-sensitive mitochondrial NAD+ levels dictate cell survivalGrowth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humansSRT1720 improves survival and healthspan of obese miceChronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in ratsResveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life spanIntermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intakeThe search for antiaging interventions: from elixirs to fasting regimensThe Neuromuscular Junction: Aging at the Crossroad between Nerves and MuscleA high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndromeReduced expression of MYC increases longevity and enhances healthspan.Resveratrol improves health and survival of mice on a high-calorie dietNQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast.The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistanceDeclining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during agingMitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stressVascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant responseRNA-Binding Protein AUF1 Promotes Myogenesis by Regulating MEF2C Expression LevelsImpact of Longevity Interventions on a Validated Mouse Clinical Frailty IndexSIRT1 is essential for normal cognitive function and synaptic plasticityThe SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growthConserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males.Sirtuin activation: a role for plasma membrane in the cell growth puzzleIn vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets.Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis.Determinants of serum-induced SIRT1 expression in older men: the CHAMP study.Genetic deletion of Nrf2 promotes immortalization and decreases life span of murine embryonic fibroblasts.Aging biology and novel targets for drug discovery.The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard dietEffect of caloric restriction on base-excision repair (BER) in the aging rat brain17α-estradiol attenuates neuron loss in ovariectomized Dtg AβPP/PS1 mice.Oxidative stress accumulates in adipose tissue during aging and inhibits adipogenesis.Mitochondrial ultrastructure and markers of dynamics in hepatocytes from aged, calorie restricted mice fed with different dietary fats.Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.
P50
Q24293117-BAC56653-8B64-463A-BC03-0F4450B1F0D2Q24297207-F951F985-AC03-4A73-9DDD-51A1E5075A73Q24297512-A92AAEC0-E41A-47A2-BDF7-10391E6CFFFDQ24541443-61D85C92-D27E-4B61-9840-188DEA844EA1Q24597354-D0D67AC9-55E8-4FBA-AE36-677BB7162B56Q24598129-E3509375-9369-484D-A54D-200FE6B81860Q24604312-A50BB508-8496-4D50-ACE8-47C2FCF21073Q24612868-D0FADEE0-C204-4E9F-9DEF-7CDFFB899E59Q24618226-1D21234F-D96B-4D6F-83FD-AB654A734430Q24627930-13963CD9-0B3A-41A3-8A44-8B7BCA37EF84Q24634601-0939E2DB-1176-43CD-8917-016E4FEA15C0Q24649811-977F9613-6F84-45D7-8E0C-1EEE5FE2A53FQ24674863-B8686823-C476-4D71-8DC3-E71CA7E79CEEQ26863497-AA072600-6656-45C1-A5EE-96C01D114F65Q27030836-EF1F70DB-49F6-4AFB-9D7D-8C795A5324F2Q27318209-B54BDC5A-3C27-4C0C-BA7E-C90B49F2389EQ27323151-5CD37109-EF57-41DD-8C73-21056A46DBDFQ27860950-50ED7649-1059-44F3-8319-B593557EA2D2Q27932205-0E2A486C-865C-45C2-A871-28BB440F31F9Q28116902-427DA533-8E11-4978-B5B7-42CCD5B85470Q28304473-E0692D51-B3E7-409C-993C-1598502FACE9Q28580773-D2911631-A65C-463F-853B-1442A1B1E7C8Q29347088-8EF36D8A-5AD4-4362-B486-C18F21B76B69Q29395966-DBDB4E5F-ACF6-4770-90A7-C446A668D363Q30362276-7EB31AEB-3C5D-4A05-979D-2C63081BBD7AQ30496047-9F929D7D-2C1C-4857-9839-621E2C40777CQ33328513-25CC996E-A6A6-44F0-A71A-7C9A5D86A79DQ33342831-9AC7C44D-8235-4D3E-9A1F-CEC927DFDCD9Q33354469-C42AA855-0346-4D67-B52E-6794A6143F92Q33369419-9D060692-7171-4E79-9D2F-1DBD34236098Q33434498-6D352366-B7D6-4DF4-BE15-6BF62E8DC9C4Q33557923-CA1E5225-3009-4B0C-AD90-C77050A0326AQ33557928-73E8606A-73C8-43EA-81AF-1A342B9723E2Q33558234-92970FE8-80BD-4145-A130-127FDA2A1D87Q33566310-3B94561E-EFC7-4F5C-BD23-C2B5C4A6B87DQ33679304-4FEABA9B-E7F1-4070-B814-E9B7FF122D67Q33825736-745EE33B-DFD0-4FE2-A81C-3602D576B67EQ33886740-0378A706-B319-4469-BE1E-328B48D80C95Q33925058-91B64C16-D1DA-47C3-B24B-B087B5E10A03Q33994850-D638D43C-EF25-4263-B07C-E6E19AE7C95B
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Rafael de Cabo
@ast
Rafael de Cabo
@en
Rafael de Cabo
@es
Rafael de Cabo
@nl
Rafael de Cabo
@sl
type
label
Rafael de Cabo
@ast
Rafael de Cabo
@en
Rafael de Cabo
@es
Rafael de Cabo
@nl
Rafael de Cabo
@sl
prefLabel
Rafael de Cabo
@ast
Rafael de Cabo
@en
Rafael de Cabo
@es
Rafael de Cabo
@nl
Rafael de Cabo
@sl
P1053
J-5230-2016
P106
P1153
6602763291
P21
P31
P3829
P496
0000-0002-3354-2442
0000-0003-2830-5693