Binding of manumycin A inhibits IkappaB kinase beta activity
about
Developing irreversible inhibitors of the protein kinase cysteinomeBiochemical and genetic insights into asukamycin biosynthesis.Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179.Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.Biosynthesis of colabomycin E, a new manumycin-family metabolite, involves an unusual chain-length factor.Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells.Angiotensin II Reduces Lipoprotein Lipase Expression in Visceral Adipose Tissue via Phospholipase C β4 Depending on Feeding but Increases Lipoprotein Lipase Expression in Subcutaneous Adipose Tissue via c-Src.Mutation of cysteine 46 in IKK-beta increases inflammatory responses.NF-kappaB signaling, liver disease and hepatoprotective agents.Chemical biology of inflammatory cytokine signaling.Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases.Withaferin A and its potential role in glioblastoma (GBM).Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells.Epoxyquinol B, a naturally occurring pentaketide dimer, inhibits NF-kappaB signaling by crosslinking TAK1.Withaferin A abolishes the stem cell factor-stimulated pigmentation of human epidermal equivalents by interrupting the auto-phosphorylation of c-KIT in human melanocytes.Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts.Targeting IKKβ in Cancer: Challenges and Opportunities for the Therapeutic Utilisation of IKKβ Inhibitors
P2860
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P2860
Binding of manumycin A inhibits IkappaB kinase beta activity
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Binding of manumycin A inhibits IkappaB kinase beta activity
@ast
Binding of manumycin A inhibits IkappaB kinase beta activity
@en
Binding of manumycin A inhibits IkappaB kinase beta activity
@en-gb
Binding of manumycin A inhibits IkappaB kinase beta activity
@nl
type
label
Binding of manumycin A inhibits IkappaB kinase beta activity
@ast
Binding of manumycin A inhibits IkappaB kinase beta activity
@en
Binding of manumycin A inhibits IkappaB kinase beta activity
@en-gb
Binding of manumycin A inhibits IkappaB kinase beta activity
@nl
prefLabel
Binding of manumycin A inhibits IkappaB kinase beta activity
@ast
Binding of manumycin A inhibits IkappaB kinase beta activity
@en
Binding of manumycin A inhibits IkappaB kinase beta activity
@en-gb
Binding of manumycin A inhibits IkappaB kinase beta activity
@nl
P2093
P2860
P50
P356
P1476
Binding of manumycin A inhibits IkappaB kinase beta activity
@en
P2093
Hua-Jun He
Rui-Jing Zhao
Sanjay K Pandey
Sutapa Kole
Tie-Nian Zhu
Yong-Kook Kwon
P2860
P304
P356
10.1074/JBC.M511878200
P407
P577
2005-11-30T00:00:00Z