Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.
about
Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.A disease-associated Aifm1 variant induces severe myopathy in knockin mice.Towards a therapy for mitochondrial disease: an updateRapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis
P2860
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.
description
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Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.
@en
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.
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label
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.
@en
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.
@nl
prefLabel
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.
@en
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.
@nl
P2093
P2860
P356
P1476
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome
@en
P2093
Eric A Schon
Martin Javors
Michio Hirano
Owen Skinner
Rohit Sharma
Vamsi Mootha
P2860
P304
P356
10.1093/HMG/DDX341
P577
2017-12-01T00:00:00Z