about
A detailed picture of the origin of the Australian dingo, obtained from the study of mitochondrial DNAA jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomesComparative analysis of hepatitis C virus phylogenies from coding and non-coding regions: the 5' untranslated region (UTR) fails to classify subtypesClassification of hepatitis C virus and human immunodeficiency virus-1 sequences with the branching indexGenetic evidence for an East Asian origin of domestic dogsmtDNA data indicate a single origin for dogs south of Yangtze River, less than 16,300 years ago, from numerous wolvesRecombination rate and selection strength in HIV intra-patient evolutionDynamics of HIV-1 quasispecies during antiviral treatment dissected using ultra-deep pyrosequencingThe evolutionary rate dynamically tracks changes in HIV-1 epidemics: application of a simple method for optimizing the evolutionary rate in phylogenetic trees with longitudinal dataUnequal evolutionary rates in the human immunodeficiency virus type 1 (HIV-1) pandemic: the evolutionary rate of HIV-1 slows down when the epidemic rate increasesRare HIV-1 Subtype J Genomes and a New H/U/CRF02_AG Recombinant Genome Suggests an Ancient Origin of HIV-1 in AngolaThe role of recombination in the emergence of a complex and dynamic HIV epidemic.On the contribution of Angola to the initial spread of HIV-1.PCR-induced transitions are the major source of error in cleaned ultra-deep pyrosequencing dataDynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression.Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo.Phylodynamic Inference across Epidemic Scales.Evolution of the human immunodeficiency virus type 2 envelope in the first years of infection is associated with the dynamics of the neutralizing antibody response.Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing.Viral linkage in HIV-1 seroconverters and their partners in an HIV-1 prevention clinical trial.HIV-2 genetic evolution in patients with advanced disease is faster than that in matched HIV-1 patients.Daily sampling of an HIV-1 patient with slowly progressing disease displays persistence of multiple env subpopulations consistent with neutralityHIV classification using the coalescent theory.Timing and order of transmission events is not directly reflected in a pathogen phylogeny.Reduced evolutionary rates in HIV-1 reveal extensive latency periods among replicating lineagesShort communication: HIV-1 Nef protein carries multiple epitopes suitable for induction of cellular immunity for an HIV vaccine in AfricaImproved HIV-1 viral load determination based on reverse transcriptase activity recovered from human plasma.Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control.Dynamics of two separate but linked HIV-1 CRF01_AE outbreaks among injection drug users in Stockholm, Sweden, and Helsinki, FinlandTowards estimation of HIV-1 date of infection: a time-continuous IgG-model shows that seroconversion does not occur at the midpoint between negative and positive tests.A multiple-alignment based primer design algorithm for genetically highly variable DNA targetsjpHMM at GOBICS: a web server to detect genomic recombinations in HIV-1.Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection.PrimerDesign-M: a multiple-alignment based multiple-primer design tool for walking across variable genomes.Recombination Enhances HIV-1 Envelope Diversity by Facilitating the Survival of Latent Genomic Fragments in the Plasma Virus Population.Trends of HIV-1 incidence with credible intervals in Sweden 2002-09 reconstructed using a dynamic model of within-patient IgG growthSCoRS--A Method Based on Stability for Feature Selection and Mapping inNeuroimaging [corrected].Phylogenetic analysis of the Latvian HIV-1 epidemic.Agent-based and phylogenetic analyses reveal how HIV-1 moves between risk groups: injecting drug users sustain the heterosexual epidemic in Latvia.Quantitative experimental determination of primer-dimer formation risk by free-solution conjugate electrophoresis.
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description
Biologe und Biophysiker
@de
researcher
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wetenschapper
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name
Thomas Leitner
@de
Thomas Leitner
@en
Thomas Leitner
@nl
type
label
Thomas Leitner
@de
Thomas Leitner
@en
Thomas Leitner
@nl
prefLabel
Thomas Leitner
@de
Thomas Leitner
@en
Thomas Leitner
@nl
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P1960
d_MOLb0AAAAJ
P21
P31
P496
0000-0001-8160-2588