P1346
P138
Antitumor activity of a pyrrole-imidazole polyamideSuppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamideA sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphomaStructure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motifCrystal structures of nucleosome core particles in complex with minor groove DNA-binding ligandsAllosteric modulation of DNA by small moleculesStructural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor BindingMolecular basis of antibiotic multiresistance transfer in Staphylococcus aureusRecognition of the DNA minor groove by pyrrole-imidazole polyamidesRecognition of ten base pairs of DNA by head-to-head hairpin dimersDNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugateTargeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrrole-imidazole polyamides.Search for the optimal linker in tandem hairpin polyamidesCell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugateArresting cancer proliferation by small-molecule gene regulationMinimization of a protein-DNA dimerizerParallel synthesis of H-pin polyamides by alkene metathesis on solid phase.Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates.Nuclear localization of pyrrole-imidazole polyamide-fluorescein conjugates in cell culture.Improved nuclear localization of DNA-binding polyamides.Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cellsCompletion of a Programmable DNA-Binding Small Molecule LibraryModifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture.Molecular recognition of the nucleosomal "supergroove".Temperature-sensitive protein-DNA dimerizers.A C-14 labeled Py-Im polyamide localizes to a subcutaneous prostate cancer tumor.Defining the sequence-recognition profile of DNA-binding molecules.Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint response.Promoter scanning for transcription inhibition with DNA-binding polyamides.Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates.Tumor xenograft uptake of a pyrrole-imidazole (Py-Im) polyamide varies as a function of cell line grafted.Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.Synthesis of cyclic Py-Im polyamide libraries.Addressing single molecules on DNA nanostructuresDNA sequence selectivity of hairpin polyamide turn unitsQuantitative microarray profiling of DNA-binding moleculesFluorescent sequence-specific dsDNA binding oligomersDNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia.Design of sequence-specific DNA binding molecules for DNA methyltransferase inhibition.
P50
Q24628320-E1242D30-A623-492E-B269-F9AAABC00D1DQ24669875-C7D94B35-F66C-4187-9A29-A3CD50E7526FQ26780141-447784ED-9EA9-42CC-A11D-A4034C2B4B07Q27639211-53357D44-F8FB-4FF3-A08E-2ACCE9490003Q27640403-047DE3AD-3EE8-4F08-8F2A-25F544E5237EQ27656940-6DFE79AB-D23C-434E-A2C4-1671DD8EA87FQ27664249-9333BE81-F928-4AEF-8C74-A53ED10ABF4BQ27676045-9F7B9794-3389-43C0-9189-C1D31902C9B3Q28182798-D2B4EC89-E7AD-4C51-BD30-349481BBAF4CQ28203854-1D076D84-0739-45E0-901D-4A91838558C4Q28208906-8F0C15DC-CAC2-4CD5-82E2-B0F0CBFE03FFQ28213125-969E6B4C-09C0-439B-92E1-C27CD5A16657Q28216488-5167E1CB-4A09-40B0-9593-365BD01F8F23Q28219094-B0990649-AA68-481E-807A-10E40379CE65Q28294374-BB842E26-974E-43AE-868D-66E2B80D3B28Q30829624-F9AE1A54-1D25-46CB-A002-1F036713F048Q30917527-7A20C4A3-52AD-46D0-ADDF-3A6183E39C2AQ31099903-E89A7768-A03A-4E3A-816E-9DA2F262924FQ33193534-D4FDD969-5D73-4267-AA52-2824AD6D6891Q33266897-8CF0E5F9-878E-4C0B-82D4-D75A5E2A4265Q33331950-EB8279A7-D04B-4CA7-87FD-0B9FA79E3CAAQ33340423-84578BC7-ED9A-4FAB-A73A-D6D0FA9C9BCEQ33348532-FB451C6A-3228-4093-8FA4-0B22F3A4BC4FQ33477522-D85248E3-A58A-4265-8195-1331DCC0B4DFQ33781158-74B139C8-95E5-47F3-B087-1A21B84C6EA9Q33935824-D7807058-3C7B-4431-A389-B79508ACD9C8Q34053649-1E79379E-70F4-4E80-9642-F6F89DCC163BQ34304813-D7C6237A-2AB8-4F8E-9828-EB9506CFECF0Q34313126-714620C1-0F6C-4965-9B86-1748D99212BEQ34323978-7A7D6792-C82A-41BC-889D-3EE12F326511Q34334052-47FCC9D0-780F-4289-99B0-DA71E2C185E0Q34394131-93FA650D-7388-4D48-A8AC-AE6C3680C41CQ34421960-E94FB6E8-B6DE-44CC-B78D-17F08FE00529Q34459196-3C74DA9A-ED7E-40ED-83A0-4910D222A55DQ34673772-c6fed5e0-4945-1222-ef6e-7bea4afec717Q34708077-AAF5B507-9F15-4690-9E7F-2D95BC270928Q34732038-EC241BB5-6C24-460F-9C07-1771074CE03BQ34735683-851569F8-684F-4FBA-A633-5C2D857E716DQ34984370-56DD91B2-5F5D-4AD1-B570-F5D7DCFE249BQ35087309-A5874B7B-5B3E-4539-8BE2-BFF3563AAFF1
P50
description
Ameerika Ühendriikide keemik
@et
American chemist
@en
Amerikaans scheikundige
@nl
US-amerikanischer Chemiker
@de
Usana kemiisto
@io
amerikansk kemiker
@da
amerikansk kemist
@sv
amerikansk kjemikar
@nn
amerikansk kjemiker
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ceimiceoir Meiriceánach
@ga
name
Peter Dervan
@ast
Peter Dervan
@ca
Peter Dervan
@da
Peter Dervan
@de
Peter Dervan
@en
Peter Dervan
@es
Peter Dervan
@fr
Peter Dervan
@ga
Peter Dervan
@it
Peter Dervan
@nb
type
label
Peter Dervan
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Peter Dervan
@ca
Peter Dervan
@da
Peter Dervan
@de
Peter Dervan
@en
Peter Dervan
@es
Peter Dervan
@fr
Peter Dervan
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Peter Dervan
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Peter Dervan
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altLabel
Peter B. Dervan
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Peter B. Dervan
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Peter Brendan Dervan
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prefLabel
Peter Dervan
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Peter Dervan
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Peter Dervan
@da
Peter Dervan
@de
Peter Dervan
@en
Peter Dervan
@es
Peter Dervan
@fr
Peter Dervan
@ga
Peter Dervan
@it
Peter Dervan
@nb
P166
P463
P69
P214
P227
P244
P106
P1263
977/000168473
P166
P185
P19
P21
P213
0000 0001 2344 9036
P214
P227
P2381
P244
no2011101591