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Q35746425-5D6695CD-9ABD-4432-BCA9-4DE3DED6CDB0
Q35746425-5D6695CD-9ABD-4432-BCA9-4DE3DED6CDB0
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http://www.wikidata.org/entity/statement/Q35746425-5D6695CD-9ABD-4432-BCA9-4DE3DED6CDB0
Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
P2860
Q35746425-5D6695CD-9ABD-4432-BCA9-4DE3DED6CDB0
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35746425-5D6695CD-9ABD-4432-BCA9-4DE3DED6CDB0
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wasDerivedFrom
31564ad30e8b9a9d0028973e9b1eafe84475bb0d
P2860
The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism