Inverse agonist

Inverse agonist

In pharmacology, an inverse agonist is a drug that binds to the same receptor as an agonist but induces a pharmacological response opposite to that of the agonist. A neutral antagonist has no activity in the absence of an agonist or inverse agonist but can block the activity of either. Inverse agonists have opposite actions to those of agonists but the effects of both of these can be blocked by antagonists. The efficacy of a full agonist is by definition 100%, a neutral antagonist has 0% efficacy, and an inverse agonist has < 0% (i.e., negative) efficacy.
Thing
http://dbpedia.org/resource/Inverse_agonist
Agonist (disambiguation)
Wikipage disambiguates
Inverse_agonist
primaryTopic

Inverse agonist

In pharmacology, an inverse agonist is a drug that binds to the same receptor as an agonist but induces a pharmacological response opposite to that of the agonist. A neutral antagonist has no activity in the absence of an agonist or inverse agonist but can block the activity of either. Inverse agonists have opposite actions to those of agonists but the effects of both of these can be blocked by antagonists. The efficacy of a full agonist is by definition 100%, a neutral antagonist has 0% efficacy, and an inverse agonist has < 0% (i.e., negative) efficacy.
Thing
http://dbpedia.org/resource/Inverse_agonist
has abstract
Als inverse Agonisten werden i ...... n oder Überexpression) zeigen.
@de
En farmacología, el agonista i ...... del agonista inverso es < 0%.
@es
En pharmacologie, un agoniste ...... t sédatif des benzodiazépines.
@fr
In pharmacology, an inverse ag ...... 0% (i.e., negative) efficacy.
@en
No campo da farmacologia, um a ...... sta inverso é < 0% (negativa).
@pt
Odwrotny agonista – substancja ...... idowych) * czynnik Ro15-4513.
@pl
Обра́тный агони́ст (англ. inve ...... положен вызываемому агонистом.
@ru
У фармакології зворотний агоні ...... оніст < 0 % (тобто негативну).
@uk
反激动剂（英語：inverse agonist）在药理学中是 ...... 沉默拮抗剂本身没有任何活性，但能阻止激动剂和反激动剂的活性。
@zh
受容体逆作動薬（じゅようたいぎゃくさどうやく、inverse ...... であるとすると、逆作動薬の活性は0%未満（マイナス）である。
@ja
Link from a Wikipage to an external page
Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
Link from a Wikipage to another Wikipage
wikiPageUsesTemplate
subject
hypernym
type
comment
Als inverse Agonisten werden i ...... ls Inversagonisten bezeichnet.
@de
En farmacología, el agonista i ...... loquear la actividad de ambos.
@es
En pharmacologie, un agoniste ...... ifiée d'activité constitutive.
@fr
In pharmacology, an inverse ag ...... 0% (i.e., negative) efficacy.
@en
No campo da farmacologia, um a ...... bloquear a atividade de ambos.
@pt
Odwrotny agonista – substancja ...... owana przez odwrotne agonisty.
@pl
Обра́тный агони́ст (англ. inve ...... ологическим эффектам агониста.
@ru
У фармакології зворотний агоні ...... оніст < 0 % (тобто негативну).
@uk
反激动剂（英語：inverse agonist）在药理学中是 ...... 沉默拮抗剂本身没有任何活性，但能阻止激动剂和反激动剂的活性。
@zh
受容体逆作動薬（じゅようたいぎゃくさどうやく、inverse ...... であるとすると、逆作動薬の活性は0%未満（マイナス）である。
@ja
label
Agonista inverso
@es
Agonista inverso
@pt
Agoniste inverse
@fr
Inverse agonist
@en
Inverser Agonist
@de
Odwrotny agonista
@pl
Зворотний агоніст
@uk
Обратный агонист
@ru
反激动剂
@zh
受容体逆作動薬
@ja
differentFrom
sameAs
wasDerivedFrom
isPrimaryTopicOf