about
P688
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overloadBone morphogenetic protein signaling by hemojuvelin regulates hepcidin expressionBmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levelsRepulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual systemSuppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasisSmad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overloadTwo BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsivenessHemojuvelin is essential for transferrin-dependent and transferrin-independent hepcidin expression in mice
P921
Q24312272-5589D4D0-2AC2-4387-A3A5-6A334D64C5F6Q24316099-11CCD884-6B4B-4814-B4F4-770E43B7A6D6Q27310179-94BCC0D7-FD35-4F6F-8930-30C1D1C631A8Q27333705-5DBED2D2-9CFC-4E27-9A17-AADBA57CDD8BQ28506752-40BE0F96-3DEE-4CD8-AE50-D54ED5C921A2Q28507491-35B76FCE-A140-4471-BE75-60FCEBE8F929Q28509930-3B5809B5-831A-4C4E-BC9F-E82A4C5C31EDQ28587039-190C52C5-88DC-4ECA-84EE-89E79058D24EQ28588325-050AA3B1-8A07-46C0-AC5C-23188F113CC6Q28590419-085497AD-CC20-47C0-A576-34BE39BFA65E
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Hemochromatosis type 2 (juvenile)
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Hemojuvelin BMP co-receptor
@en
Hemojuvelin BMP co-receptor
@nl
type
label
Hemojuvelin BMP co-receptor
@en
Hemojuvelin BMP co-receptor
@nl
altLabel
Hfe2
@en
Hjv
@en
RGM domain family member C
@en
hemochromatosis type 2 (juvenile) (human homolog)
@en
hemochromatosis type 2 protein homolog
@en
hemojuvelin BMP coreceptor
@en
hemojuvelin
@en
repulsive guidance molecule C
@en
prefLabel
Hemojuvelin BMP co-receptor
@en
Hemojuvelin BMP co-receptor
@nl
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ENSMUSP00000046659