Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis
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Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasisHepcidin: A Promising Therapeutic Target for Iron Disorders: A Systematic ReviewHepcidin and iron homeostasisMurine mutants in the study of systemic iron metabolism and its disorders: an update on recent advancesBMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelinEffect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and RatsStructure of the Repulsive Guidance Molecule (RGM)-Neogenin Signaling HubHepcidin and iron regulation, 10 years later.Iron regulation by hepcidinSuppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 proteinA novel rat model of hereditary hemochromatosis due to a mutation in transferrin receptor 2Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis.Neogenin as a receptor for early cell fate determination in preimplantation mouse embryos.Soluble repulsive guidance molecule c/hemojuvelin is a broad spectrum bone morphogenetic protein (BMP) antagonist and inhibits both BMP2- and BMP6-mediated signaling and gene expression.Neogenin regulation of BMP-induced canonical Smad signaling and endochondral bone formation.Hepcidin in beta-thalassemia.Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin.Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.Low intracellular iron increases the stability of matriptase-2.Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in miceHereditary hemochromatosis and transferrin receptor 2VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.A systems biology approach to iron metabolism.Anti-repulsive Guidance Molecule C (RGMc) Antibodies Increases Serum Iron in Rats and Cynomolgus Monkeys by Hepcidin Downregulation.Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.Neogenin interacts with matriptase-2 to facilitate hemojuvelin cleavage.VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum.Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling.Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism.Unraveling mechanisms regulating systemic iron homeostasis.Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex.Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver.Vitamin A deficiency modulates iron metabolism independent of hemojuvelin (Hfe2) and bone morphogenetic protein 6 (Bmp6) transcript levels.Out of balance--systemic iron homeostasis in iron-related disordersThe neogenin/DCC homolog UNC-40 promotes BMP signaling via the RGM protein DRAG-1 in C. elegansHepcidin in neoplastic disease.The liver: conductor of systemic iron balance.Molecular basis of iron-loading disorders.Control of systemic iron homeostasis by the hemojuvelin-hepcidin axis.
P2860
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P2860
Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis
description
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im April 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/04/15)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/04/15)
@nl
наукова стаття, опублікована у квітні 2010
@uk
مقالة علمية (نشرت في 15-4-2010)
@ar
name
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@ast
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@en
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@nl
type
label
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@ast
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@en
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@nl
prefLabel
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@ast
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@en
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@nl
P2093
P2860
P921
P3181
P1433
P1476
Neogenin inhibits HJV secretio ...... xpression and iron homeostasis
@en
P2093
Cai-Xia Xi
Dae-Hoon Lee
Jian-Xin Xie
Li-Juan Zhou
Wen-Cheng Xiong
Zheng Zhou
P2860
P304
P3181
P356
10.1182/BLOOD-2009-11-251199
P407
P50
P577
2010-01-11T00:00:00Z