The pseudo GTPase CENP-M drives human kinetochore assemblyMechanism of CDK5/p25 binding by CDK inhibitorsCrystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointEvidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction.The Mad2 conformational dimer: structure and implications for the spindle assembly checkpointA small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora BMolecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell divisionStructural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interactionArchitecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochoreCrystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitinDeterminants of conformational dimerization of Mad2 and its inhibition by p31cometStructural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machineryMad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochoresSgt1 is required for human kinetochore assemblySH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55Progress in the structural and functional characterization of kinetochoresThe Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingMolecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and AstrinImplications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex.Structure and regulation of the CDK5-p25(nck5a) complexCrystal structure of a Src-homology 3 (SH3) domainGSK-3-selective inhibitors derived from Tyrian purple indirubinsThe structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephalyDiscovery of selective aminothiazole aurora kinase inhibitorsReversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cellsMolecular basis of drug resistance in aurora kinasesCrystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organizationThe Ndc80 kinetochore complex forms oligomeric arrays along microtubulesStructure of the HECT:ubiquitin complex and its role in ubiquitin chain elongationCrystal Structure of Human Aurora B in Complex with INCENP and VX-680Selective Aurora Kinase Inhibitors Identified Using a Taxol-Induced Checkpoint Sensitivity ScreenBub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signalingModular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organizationHigh-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptidesCrystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrinCrystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunitThe structure of the GTPase-activating domain from p50rhoGAPAtomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linkerThe spindle-assembly checkpoint in space and time
P50
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P50
description
Italiaans onderzoeker
@nl
Italian biologist
@en
Italian biologist
@en-ca
Italian biologist
@en-gb
bitheolaí Iodálach
@ga
biólogo italiano
@es
investigador italianu
@ast
عالم أحياء إيطالي
@ar
ইতালীয় জীববিজ্ঞানী
@bn
name
Andrea Musacchio
@ast
Andrea Musacchio
@ca
Andrea Musacchio
@de
Andrea Musacchio
@en
Andrea Musacchio
@es
Andrea Musacchio
@fr
Andrea Musacchio
@ga
Andrea Musacchio
@it
Andrea Musacchio
@nl
Andrea Musacchio
@sl
type
label
Andrea Musacchio
@ast
Andrea Musacchio
@ca
Andrea Musacchio
@de
Andrea Musacchio
@en
Andrea Musacchio
@es
Andrea Musacchio
@fr
Andrea Musacchio
@ga
Andrea Musacchio
@it
Andrea Musacchio
@nl
Andrea Musacchio
@sl
prefLabel
Andrea Musacchio
@ast
Andrea Musacchio
@ca
Andrea Musacchio
@de
Andrea Musacchio
@en
Andrea Musacchio
@es
Andrea Musacchio
@fr
Andrea Musacchio
@ga
Andrea Musacchio
@it
Andrea Musacchio
@nl
Andrea Musacchio
@sl
P227
P101
P19
P21
P214
3371148632937230630003
P227
1124616128
P27
P31
P496
0000-0003-2362-8784
P569
1964-07-11T00:00:00Z