Tau interacts with src-family non-receptor tyrosine kinases
about
A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's diseaseProtein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.Is tau ready for admission to the prion club?The MAP2/Tau family of microtubule-associated proteinsTau Oligomers: The Toxic Player at Synapses in Alzheimer's DiseaseBreaking the Code of Amyloid-β OligomersTangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemTau-targeted treatment strategies in Alzheimer's diseaseTau and tauopathiesMaintenance of synaptic stability requires calcium-independent phospholipase A₂ activityTau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in MiceTau physiology and pathomechanisms in frontotemporal lobar degenerationTau Biology and Tau-Directed Therapies for Alzheimer's DiseaseGene organization, evolution and expression of the microtubule-associated protein ASAP (MAP9)Direct interaction and functional coupling between human 5-HT6 receptor and the light chain 1 subunit of the microtubule-associated protein 1B (MAP1B-LC1)Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease.Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domainAlphaScreen HTS and live-cell bioluminescence resonance energy transfer (BRET) assays for identification of Tau-Fyn SH3 interaction inhibitors for Alzheimer disease.Intermediate filament-associated cytolinker plectin 1c destabilizes microtubules in keratinocytesProline substitutions and threonine pseudophosphorylation of the SH3 ligand of 18.5-kDa myelin basic protein decrease its affinity for the Fyn-SH3 domain and alter process development and protein localization in oligodendrocytesAmyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease.Microtubule-mediated Src tyrosine kinase trafficking in neuronal growth cones.Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn.Neuromuscular synapse integrity requires linkage of acetylcholine receptors to postsynaptic intermediate filament networks via rapsyn-plectin 1f complexes.Tau protein is essential for stress-induced brain pathologyRoles of tau protein in health and disease.Phosphoregulation of Tau modulates inhibition of kinesin-1 motility.Phosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture.PTL-1 regulates neuronal integrity and lifespan in C. elegans.Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease.The role of the lipid bilayer in tau aggregationTau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding.The role of tau kinases in Alzheimer's disease.Increased Protein Tyrosine Phosphorylation in Apoptotic Neural Cell Death Due to Microtubule Perturbations.Adaptors for disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease.Fyn inhibition rescues established memory and synapse loss in Alzheimer mice.The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activitiesTwo motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone.
P2860
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P2860
Tau interacts with src-family non-receptor tyrosine kinases
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Tau interacts with src-family non-receptor tyrosine kinases
@ast
Tau interacts with src-family non-receptor tyrosine kinases
@en
Tau interacts with src-family non-receptor tyrosine kinases
@nl
type
label
Tau interacts with src-family non-receptor tyrosine kinases
@ast
Tau interacts with src-family non-receptor tyrosine kinases
@en
Tau interacts with src-family non-receptor tyrosine kinases
@nl
prefLabel
Tau interacts with src-family non-receptor tyrosine kinases
@ast
Tau interacts with src-family non-receptor tyrosine kinases
@en
Tau interacts with src-family non-receptor tyrosine kinases
@nl
P2093
P3181
P1476
Tau interacts with src-family non-receptor tyrosine kinases
@en
P2093
P304
P3181
P407
P478
111 ( Pt 21)
P577
1998-11-01T00:00:00Z