Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
about
Regulation of p53 activity in nuclear bodies by a specific PML isoformThe human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding proteinThe corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradationIsolation and characterization of a new nucleolar protein, Nrap, that is conserved from yeast to humansNucleolar retention of a translational C/EBPalpha isoform stimulates rDNA transcription and cell sizeThe mechanism of nuclear export of Smad3 involves exportin 4 and RanPhosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53RNF38 encodes a nuclear ubiquitin protein ligase that modifies p53MOZ increases p53 acetylation and premature senescence through its complex formation with PMLA novel ARF-binding protein (LZAP) alters ARF regulation of HDM2LZAP inhibits p38 MAPK (p38) phosphorylation and activity by facilitating p38 association with the wild-type p53 induced phosphatase 1 (WIP1)Functional architecture in the cell nucleusYeast Pescadillo is required for multiple activities during 60S ribosomal subunit synthesis.DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms.Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transitionThe CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1Inhibition of HDM2 and activation of p53 by ribosomal protein L23Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionEssential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activationp19ARF determines the balance between normal cell proliferation rate and apoptosis during mammary gland developmentThe nucleolus under stressTwist is a potential oncogene that inhibits apoptosisMolecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancersRibosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathwayWerner protein recruits DNA polymerase delta to the nucleolusUbiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear importRapid asymmetric evolution of a dual-coding tumor suppressor INK4a/ARF locus contradicts its functionp14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomesp19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathwaysNucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1The SUMO-specific protease SENP5 is required for cell division.The transcriptional role of PML and the nuclear bodyAn N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivoMultiple interacting domains contribute to p14ARF mediated inhibition of MDM2Oligomerization of the human ARF tumor suppressor and its response to oxidative stressMdmX binding to ARF affects Mdm2 protein stability and p53 transactivationThe Ki-67 protein interacts with members of the heterochromatin protein 1 (HP1) family: a potential role in the regulation of higher-order chromatin structureAssociation of p14ARF with the p120E4F transcriptional repressor enhances cell cycle inhibitionBeta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2
P2860
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P2860
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@ast
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@en
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@en-gb
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@nl
type
label
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@ast
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@en
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@en-gb
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@nl
prefLabel
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@ast
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@en
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@en-gb
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@nl
P1433
P1476
Mutations in human ARF exon 2 ...... nuclear export of MDM2 and p53
@en
P304
P356
10.1016/S1097-2765(00)80351-2
P407
P577
1999-05-01T00:00:00Z