Werner protein recruits DNA polymerase delta to the nucleolus
about
Werner SyndromeWerner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activityDistinctive activities of DNA polymerases during human DNA replicationThe spectrum of WRN mutations in Werner syndrome patientsIdentification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta.A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigenRoles of Werner syndrome protein in protection of genome integrityModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesThe Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase deltaHuman premature aging, DNA repair and RecQ helicasesCrystal structure of the HRDC domain of human Werner syndrome protein, WRNIdentification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigenRegulation of the Werner helicase through a direct interaction with a subunit of protein kinase AReconstitution of human DNA polymerase delta using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzymeThe processing of Holliday junctions by BLM and WRN helicases is regulated by p53Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase deltaThe Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δPOLD1 Germline Mutations in Patients Initially Diagnosed with Werner SyndromeAge-dependent down-regulation of DNA polymerase δ1 in human lymphocytesWerner syndrome: Clinical features, pathogenesis and potential therapeutic interventionsA novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase deltaDirect interaction of the spinal muscular atrophy disease protein SMN with the small nucleolar RNA-associated protein fibrillarin.RecQ helicases: guardian angels of the DNA replication fork.DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D.Quantitative nucleolar proteomics reveals nuclear re-organization during stress- induced senescence in mouse fibroblast.Acetylation of Werner syndrome protein (WRN): relationships with DNA damage, DNA replication and DNA metabolic activities.The nucleolusThe Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.Further characterization of human DNA polymerase delta interacting protein 38.Werner protein protects nonproliferating cells from oxidative DNA damageTelomeres, chromosome instability and cancerThe Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks.Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.The Werner syndrome protein promotes CAG/CTG repeat stability by resolving large (CAG)(n)/(CTG)(n) hairpinsMechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stabilityFunctional deficit associated with a missense Werner syndrome mutationCentral role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage.Telomeres do the (un)twist: helicase actions at chromosome termini.Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation.
P2860
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P2860
Werner protein recruits DNA polymerase delta to the nucleolus
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Werner protein recruits DNA polymerase delta to the nucleolus
@ast
Werner protein recruits DNA polymerase delta to the nucleolus
@en
Werner protein recruits DNA polymerase delta to the nucleolus
@nl
type
label
Werner protein recruits DNA polymerase delta to the nucleolus
@ast
Werner protein recruits DNA polymerase delta to the nucleolus
@en
Werner protein recruits DNA polymerase delta to the nucleolus
@nl
prefLabel
Werner protein recruits DNA polymerase delta to the nucleolus
@ast
Werner protein recruits DNA polymerase delta to the nucleolus
@en
Werner protein recruits DNA polymerase delta to the nucleolus
@nl
P2093
P2860
P356
P1476
Werner protein recruits DNA polymerase delta to the nucleolus
@en
P2093
P2860
P304
P356
10.1073/PNAS.97.21.11365
P407
P577
2000-10-10T00:00:00Z