Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors
about
Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation.Recruitment of the class II phosphoinositide 3-kinase C2beta to the epidermal growth factor receptor: role of Grb2Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease modelsTopographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiationPhosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?Phosphoinositides: tiny lipids with giant impact on cell regulationCrystal structures of PI3K-C2α PX domain indicate conformational change associated with ligand bindingDifferential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagyThe activation of nuclear phosphoinositide 3-kinase C2beta in all-trans-retinoic acid-differentiated HL-60 cellsDifferential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytesEpidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinasePI3K/PTEN signaling in angiogenesis and tumorigenesisInhibition of class II phosphoinositide 3-kinase gamma expression by p185(Bcr-Abl) contributes to impaired chemotaxis and aberrant homing of leukemic cellsHepatocyte growth factor activates phosphoinositide 3-kinase C2 beta in renal brush-border plasma membranesRegulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathwayAccelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevityPhosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with DblTargeted expression of the class II phosphoinositide 3-kinase in Drosophila melanogaster reveals lipid kinase-dependent effects on patterning and interactions with receptor signaling pathways.Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.Ca2+-regulated pool of phosphatidylinositol-3-phosphate produced by phosphatidylinositol 3-kinase C2alpha on neurosecretory vesiclesThe class II phosphoinositide 3-kinase C2beta is not essential for epidermal differentiationPhosphoinositide 3-kinase inhibition in cancer treatment.Identification and Validation of a Putative Polycomb Responsive Element in the Human GenomePhosphatidylinositol 3-kinase, class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesisInvolvement of class II phosphoinositide 3-kinase α-isoform in antigen-induced degranulation in RBL-2H3 cells.Intersectin 1 is required for neuroblastoma tumorigenesis.Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.Inhibitory role of alpha 6 beta 4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on alpha 3 beta 1 integrin.Emerging roles of phosphatidylinositol 3-monophosphate as a dynamic lipid second messenger.Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression.Vascular endothelial growth factor acts through novel, pregnancy-enhanced receptor signalling pathways to stimulate endothelial nitric oxide synthase activity in uterine artery endothelial cells.The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics.Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death.Gene delivery to Nile tilapia cells for transgenesis and the role of PI3K-c2α in angiogenesisInsights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease.How phosphoinositide 3-phosphate controls growth downstream of amino acids and autophagy downstream of amino acid withdrawal.Targeting PI3K in Cancer: Any Good News?PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction.A role for the Ca(2+)-dependent tyrosine kinase Pyk2 in tonic depolarization-induced vascular smooth muscle contraction.
P2860
Q24534893-E4994525-C980-4342-8201-2E305A379A96Q24548332-E79097FB-EF6A-4896-A0BA-FAD68F6B8866Q24673667-9FA967A4-2DBC-4B1B-B470-10EE83E85686Q24797020-0EBCFCB6-2DF1-46EC-B958-CB3211FD2632Q24801684-E68B5290-50E8-4077-B520-269B2161DD2EQ27012953-3F908D32-1058-4831-A778-52376237BB03Q27649974-19427AF5-AC76-4B24-9F56-27F74373FF74Q28081735-F6C431A1-863C-45D7-B9DE-FAAD9CE37D4CQ28206327-6A56CCE4-45CA-42FB-8DD9-F74DACA82181Q28360375-AE0F200F-8572-4C64-AAB6-47462DE3AD7DQ28365466-7B03A375-FB0E-4FBE-9A08-D7617D3D5637Q28383083-5E917122-DC7A-4F77-8AFD-3DB5034F5C2AQ28512494-7549F2B9-7E71-4B4C-9643-C054DC0FFF04Q28581772-A0912ED2-28BF-46B3-9D08-130968AAB201Q28590327-B6EBA61B-373A-4F7E-A70E-C6871250D8D5Q28704343-20233DFF-DEE6-47DE-ACCD-2E937DF60464Q28727877-8A4B04FF-C94C-49E8-98CD-F9775A6C8C28Q30164322-5BF292CA-5221-4DC2-823D-B4EEF7058B2DQ30478070-D29C6569-6E09-4988-9AD2-110AE84E3160Q30484825-BB166372-61BE-44C4-A81B-5098F692A454Q34230973-FD142C5C-8570-48A1-8926-1F54296146CEQ34481485-692B77CD-F9BE-4410-AFC7-FAE6AD0A22C8Q34785652-C590428F-7337-417D-86E2-6A7614EDCDFAQ35153937-4D1C8AC1-5E3A-442D-8FDE-B68275C9342AQ35378129-D25811D1-A73C-4686-BEC9-5682BFF8BD93Q35916258-0EE744A4-0DFC-4F55-8324-C7E42BA4856DQ36321148-50177ABB-8441-4641-89E2-32F8DF12B79CQ36360337-B3ED804A-F253-4D0D-913D-424C08369FC1Q36687961-C4241337-E503-4754-A349-65EDD5B80499Q37109753-36B8C379-3D62-45CE-ABC7-E44A1B806581Q37188408-F7E00681-A6D3-4640-B90E-47930A880E8BQ37327261-B8D096DE-6E1D-4E0B-BA7D-D098B61E0373Q37350230-5EF046FF-105D-4D99-8AAA-5F53AAA633BEQ37426342-9238385C-AC3B-46E4-A803-27AC8FFD1B94Q37710895-8C6BA974-763B-4AB9-9D6C-F846E7D5135DQ37968311-3C916048-9367-4134-8024-E84A4AD70621Q37977162-A4959637-41A5-4A2B-ADC2-44E58F2ED810Q38105322-CB24F6AF-6D72-4403-8F03-7E90BD74FA10Q38483135-6C226ACA-705F-45AA-917C-B22AEF0AACF0Q38543448-3BF07A9D-7E36-4C09-921D-814EDAE1BA0F
P2860
Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@ast
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@en
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@en-gb
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@nl
type
label
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@ast
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@en
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@en-gb
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@nl
prefLabel
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@ast
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@en
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@en-gb
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@nl
P2093
P2860
P1476
Class II phosphoinositide 3-ki ...... eptide growth factor receptors
@en
P2093
P2860
P304
P356
10.1128/MCB.20.11.3817-3830.2000
P407
P577
2000-06-01T00:00:00Z