Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
about
Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin.Heparanase 2 interacts with heparan sulfate with high affinity and inhibits heparanase activityMutations in HPSE2 cause urofacial syndromeFrom gene discovery to new biological mechanisms: heparanases and congenital urinary bladder diseaseLower urinary tract development and diseaseInvolvement of heparanase in atherosclerosis and other vessel wall pathologiesCloning and characterization of the human heparanase-1 (HPR1) gene promoter: role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activityLRIG2 mutations cause urofacial syndromeNewly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinasesLoss-of-function mutations in HPSE2 cause the autosomal recessive urofacial syndromeMechanisms of heparanase inhibitors in cancer therapy.Proteomics-based anticancer drug discovery and development.Applications of proteomics in oncology.Characterization of a novel intracellular heparanase that has a FERM domain.Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cellsRegulation of intracellular signaling by extracellular glycan remodeling.Versatile role of heparanase in inflammationThe β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and MenTumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasisTumorigenic and adhesive properties of heparanase.Genome-wide genetic associations with IFNγ response to smallpox vaccineMolecular properties and involvement of heparanase in cancer metastasis and angiogenesis.Processing of heparanase is mediated by syndecan-1 cytoplasmic domain and involves syntenin and α-actinin.Heparan sulfate proteoglycans and cancer.Clinical significance of heparanase splice variant (t5) in renal cell carcinoma: evaluation by a novel t5-specific monoclonal antibodyMammalian heparanase: what is the message?Phenotypic variability in a Hungarian patient with the 4q21 microdeletion syndrome.Urinary tract effects of HPSE2 mutations.The Profile of Heparanase Expression Distinguishes Differentiated Thyroid Carcinoma from Benign Neoplasms.Heparanase as a molecular target of cancer chemotherapy.Comparison of biomarkers in rat renal ischemia-reperfusion injury.Upregulation of heparanase in high-glucose-treated endothelial cells promotes endothelial cell migration and proliferation and correlates with Akt and extracellular-signal-regulated kinase phosphorylationSignificance of heparanase in cancer and inflammation.Contribution of eIF-4E inhibition to the expression and activity of heparanase in human colon adenocarcinoma cell line: LS-174T.Heparan sulfate proteoglycans and their binding proteins in embryo implantation and placentationHeparanase localization during palatogenesis in mice.Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas.Heparanase 2 Attenuates Head and Neck Tumor Vascularity and Growth.Impact of heparanase and the tumor microenvironment on cancer metastasis and angiogenesis: basic aspects and clinical applicationsHeparin and related drugs: beyond anticoagulant activity.
P2860
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P2860
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@ast
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@en
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@en-gb
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@nl
type
label
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@ast
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@en
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@en-gb
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@nl
prefLabel
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@ast
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@en
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@en-gb
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@nl
P2093
P356
P1476
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member
@en
P2093
C Stubberfield
E McKenzie
P304
P356
10.1006/BBRC.2000.3586
P407
P577
2000-10-05T00:00:00Z