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From gene discovery to new biological mechanisms: heparanases and congenital urinary bladder diseaseGlycosaminoglycan glycomics using mass spectrometryPathophysiology of heparan sulphate: many diseases, few drugsTowards understanding the roles of heparan sulfate proteoglycans in Alzheimer's diseaseInvolvement of heparanase in atherosclerosis and other vessel wall pathologiesThe Endothelial Glycocalyx: New Diagnostic and Therapeutic Approaches in SepsisMechanisms of heparanase inhibitors in cancer therapy.Cancer biology in diabetes.Expression of heparanase in soft tissue sarcomas of adults.Modification of heparanase gene expression in response to conditioning and LPS treatment: strong correlation to rs4693608 SNP.The β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and MenHeparanase cooperates with Ras to drive breast and skin tumorigenesisCombination therapy with low molecular weight heparin and Adriamycin results in decreased breast cancer cell metastasis in C3H mice.Anti-heparanase aptamers as potential diagnostic and therapeutic agents for oral cancer.Development of novel single-stranded nucleic acid aptamers against the pro-angiogenic and metastatic enzyme heparanase (HPSE1)Processing of heparanase is mediated by syndecan-1 cytoplasmic domain and involves syntenin and α-actinin.Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity.Activity-based probes for functional interrogation of retaining β-glucuronidases.Holothurian glycosaminoglycan inhibits metastasis and thrombosis via targeting of nuclear factor-κB/tissue factor/Factor Xa pathway in melanoma B16F10 cellsA liquid chromatography-mass spectrometry-based approach to characterize the substrate specificity of mammalian heparanase.DNA methylation of heparanase promoter influences its expression and associated with the progression of human breast cancerThe protective role of fucosylated chondroitin sulfate, a distinct glycosaminoglycan, in a murine model of streptozotocin-induced diabetic nephropathyHeparan sulfate differences in rheumatoid arthritis versus healthy seraInvolvement of Heparanase in Empyema: Implication for Novel Therapeutic ApproachesHeparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes.The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus.Breast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteoglycans.Tumor size, stage and grade alterations of urinary peptidome in RCC.Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cellsHeparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation.Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer ActivityElevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data.The potential of heparanase as a therapeutic target in cancerHeparanase regulates secretion, composition, and function of tumor cell-derived exosomesCharacterization of heparanase-induced phosphatidylinositol 3-kinase-AKT activation and its integrin dependenceProteoglycans and their roles in brain cancer.Coexpression of heparanase activity, cathepsin L, tissue factor, tissue factor pathway inhibitor, and MMP-9 in proliferative diabetic retinopathy.Heparanase 2 Attenuates Head and Neck Tumor Vascularity and Growth.Heparan sulfate and heparanase as modulators of breast cancer progressionHeparanase 2 expression inversely correlates with bladder carcinoma grade and stage.
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Significance of heparanase in cancer and inflammation.
@ast
Significance of heparanase in cancer and inflammation.
@en
type
label
Significance of heparanase in cancer and inflammation.
@ast
Significance of heparanase in cancer and inflammation.
@en
prefLabel
Significance of heparanase in cancer and inflammation.
@ast
Significance of heparanase in cancer and inflammation.
@en
P2093
P2860
P1433
P1476
Significance of heparanase in cancer and inflammation.
@en
P2093
Amichai Meirovitz
Claudio Pisano
Immanuel Lerner
Israel Vlodavsky
Michael Elkin
Phillip Beckhove
P2860
P2888
P304
P356
10.1007/S12307-011-0082-7
P577
2011-08-03T00:00:00Z