about
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair functionThe ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damageAn activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cellsErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancersHuman cyclin-dependent kinase-activating kinase exists in three distinct complexes53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancersThe BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutationsAssociation of BRCA1 with the inactive X chromosome and XIST RNARethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancerMutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition.A comprehensive analysis of PAX8 expression in human epithelial tumorsDual role of TFIIH in DNA excision repair and in transcription by RNA polymerase IIA human RNA polymerase II complex associated with SRB and DNA-repair proteinsDicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencingAngiogenic mRNA and microRNA gene expression signature predicts a novel subtype of serous ovarian cancerHigh throughput interrogation of somatic mutations in high grade serous cancer of the ovaryRationale for Developing a Specimen Bank to Study the Pathogenesis of High-Grade Serous Carcinoma: A Review of the EvidenceMesenchymal gene program-expressing ovarian cancer spheroids exhibit enhanced mesothelial clearanceCreation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array.A candidate precursor to serous carcinoma that originates in the distal fallopian tube.A molecular signature of gastric metaplasia arising in response to acute parietal cell lossThe RNA polymerase II general transcription factors: past, present, and future.Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis.Use of CA125 and HE4 serum markers to predict ovarian cancer in elevated-risk womenThe hormonal composition of follicular fluid and its implications for ovarian cancer pathogenesisElafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors.Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.Coming into focus: the nonovarian origins of ovarian cancer.Profiles of genomic instability in high-grade serous ovarian cancer predict treatment outcomeTransformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.The polyoma virus large T binding protein p150 is a transcriptional repressor of c-MYCThe distal fallopian tube: a new model for pelvic serous carcinogenesis.An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinomaModeling high-grade serous ovarian carcinogenesis from the fallopian tubeCombined therapy with thrombospondin-1 type I repeats (3TSR) and chemotherapy induces regression and significantly improves survival in a preclinical model of advanced stage epithelial ovarian cancer.CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling.Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas.Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy.The new face of ovarian cancer modeling: better prospects for detection and treatment.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Ronny Drapkin
@ast
Ronny Drapkin
@en
Ronny Drapkin
@es
Ronny Drapkin
@nl
Ronny Drapkin
@sl
type
label
Ronny Drapkin
@ast
Ronny Drapkin
@en
Ronny Drapkin
@es
Ronny Drapkin
@nl
Ronny Drapkin
@sl
prefLabel
Ronny Drapkin
@ast
Ronny Drapkin
@en
Ronny Drapkin
@es
Ronny Drapkin
@nl
Ronny Drapkin
@sl
P1053
E-9944-2016
P106
P21
P2798
P31
P3829
P496
0000-0002-6912-6977