MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes
about
Functional amyloid formation within mammalian tissue.The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and compositionThe tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesisMelanosomes--dark organelles enlighten endosomal membrane transportMelanoma-associated leukoderma - immunology in black and white?Structural basis for the presentation of tumor-associated MHC class II-restricted phosphopeptides to CD4+ T cellsPhysiological factors that regulate skin pigmentationFifteen-year quest for microphthalmia-associated transcription factor target genesMelanocytes and their diseasesIdentification of tumor-associated, MHC class II-restricted phosphopeptides as targets for immunotherapyImmunostaining for MART-1 in the interpretation of problematic intra-epidermal pigmented lesions.The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding.Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes.Diagnostic and prognostic biomarkers in melanoma.Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.Two SNPs in the SILV gene are associated with silver coat colour in ponies.Melanoma chemotherapy leads to the selection of ABCB5-expressing cellsHuman macrophages and dendritic cells can equally present MART-1 antigen to CD8(+) T cells after phagocytosis of gamma-irradiated melanoma cells.Different approaches for assaying melanosome transferSilencing of GPNMB by siRNA inhibits the formation of melanosomes in melanocytes in a MITF-independent fashionWIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition.The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease.Broadening the repertoire of melanoma-associated T-cell epitopes.Mechanisms of protein delivery to melanosomes in pigment cells.4-(Phenylsulfanyl)butan-2-One Suppresses Melanin Synthesis and Melanosome Maturation In Vitro and In Vivo.The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.Therapeutic implications of autoimmune vitiligo T cells.Immunohistochemistry and in situ hybridization in the study of human skin melanocytes.PMEL: a pigment cell-specific model for functional amyloid formationHarnessing autoimmunity (vitiligo) to treat melanoma: a myth or reality?Ex vivo derived primary melanoma cells: implications for immunotherapeutic vaccines.Formation of Pmel17 amyloid is regulated by juxtamembrane metalloproteinase cleavage, and the resulting C-terminal fragment is a substrate for gamma-secretaseComparative Depigmentation Effects of Resveratrol and Its Two Methyl Analogues in α-Melanocyte Stimulating Hormone-Triggered B16/F10 Murine Melanoma CellsThe yin and yang of amyloid: insights from α-synuclein and repeat domain of Pmel17Targeted silencing of MART-1 gene expression by RNA interference enhances the migration ability of uveal melanoma cellsESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane.FIG4, Charcot-Marie-Tooth disease, and hypopigmentation: a role for phosphoinositides in melanosome biogenesis?Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disordersThe pleiotropic roles of autophagy regulators in melanogenesis.Molecular Network Associated with MITF in Skin Melanoma Development and Progression.
P2860
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P2860
MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
MART-1 is required for the fun ...... the maturation of melanosomes
@ast
MART-1 is required for the fun ...... the maturation of melanosomes
@en
MART-1 is required for the fun ...... the maturation of melanosomes
@en-gb
MART-1 is required for the fun ...... the maturation of melanosomes
@nl
type
label
MART-1 is required for the fun ...... the maturation of melanosomes
@ast
MART-1 is required for the fun ...... the maturation of melanosomes
@en
MART-1 is required for the fun ...... the maturation of melanosomes
@en-gb
MART-1 is required for the fun ...... the maturation of melanosomes
@nl
prefLabel
MART-1 is required for the fun ...... the maturation of melanosomes
@ast
MART-1 is required for the fun ...... the maturation of melanosomes
@en
MART-1 is required for the fun ...... the maturation of melanosomes
@en-gb
MART-1 is required for the fun ...... the maturation of melanosomes
@nl
P2093
P3181
P356
P1476
MART-1 is required for the fun ...... the maturation of melanosomes
@en
P2093
Hidenori Watabe
Jacqueline Muller
Toshihiko Hoashi
Vincent J Hearing
Wilfred D Vieira
Yuji Yamaguchi
P304
P3181
P356
10.1074/JBC.M413692200
P407
P577
2005-04-08T00:00:00Z