PMEL: a pigment cell-specific model for functional amyloid formation - Wikidata - awgldk - TriplyDB

PMEL: a pigment cell-specific model for functional amyloid formation

PMEL: a pigment cell-specific model for functional amyloid formation

http://www.wikidata.org/entity/Q36788313

about

Emerging roles of extracellular vesicles in the nervous system PMEL Amyloid Fibril Formation: The Bright Steps of Pigmentation Morphological Characters and Transcriptome Profiles Associated with Black Skin and Red Skin in Crimson Snapper (Lutjanus erythropterus)The Human Disease-Associated Aβ Amyloid Core Sequence Forms Functional Amyloids in a Fungal Adhesin The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation.Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice.The PKD domain distinguishes the trafficking and amyloidogenic properties of the pigment cell protein PMEL and its homologue GPNMB.BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells.Lysosome-related organelles: unusual compartments become mainstream.Melanosomal formation of PMEL core amyloid is driven by aromatic residues.Fold modulating function: bacterial toxins to functional amyloids.Amyloidosis in alkaptonuria.Study of Exosomes Shed New Light on Physiology of Amyloidogenesis.Cellular Regulation of Amyloid Formation in Aging and Disease.Toll-like receptor 9 regulates melanogenesis through NF-κB activation.Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL.Amyloids, melanins and oxidative stress in melanomagenesis.Reduced Abundance and Subverted Functions of Proteins in Prion-Like Diseases: Gained Functions Fascinate but Lost Functions Affect Aetiology.Why are Functional Amyloids Non-Toxic in Humans?Melanomagenesis: multifaceted attacks on the genome.Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans.Functional amyloid: widespread in Nature, diverse in purpose.PIKfyve regulates melanosome biogenesis.A β-solenoid model of the Pmel17 repeat domain: insights to the formation of functional amyloid fibrils.Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson's disease.Trial watch: DNA-based vaccines for oncological indications Amyloid assembly and disassembly Length variations within the retrotransposon of canine : correlating genotype with phenotype

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PMEL: a pigment cell-specific model for functional amyloid formation

http://www.wikidata.org/entity/Q36788313

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-tw

2013年论文

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2013年论文

@zh

2013年论文

@zh-cn

name

PMEL: a pigment cell-specific model for functional amyloid formation

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PMEL: a pigment cell-specific model for functional amyloid formation

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PMEL: a pigment cell-specific model for functional amyloid formation

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Pigment Cell & Melanoma Research

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PMEL: a pigment cell-specific model for functional amyloid formation

@en

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Brenda Watt

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Graça Raposo

http://www.w3.org/2001/XMLSchema#string

Michael S Marks

http://www.w3.org/2001/XMLSchema#string

P2860

Functional amyloid formation within mammalian tissue.

A missense mutation in PMEL17 is associated with the Silver coat color in the horse

Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function

AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes

Pmel17 initiates premelanosome morphogenesis within multivesicular bodies

MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes

AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis

The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition

Localization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 function

Cloning and expression of the gene for the melanoma-associated ME20 antigen

P304

300-315

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scholarly article

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10.1111/PCMR.12067

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3

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26

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Guillaume van Niel

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2013-02-19T00:00:00Z

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235372846

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3633693

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