Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy
about
Human combinatorial antibody libraries to hepatitis B surface antigen.The second century of the antibody. Molecular perspectives in regulation, pathophysiology, and therapeutic applications.Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generationPreferential rearrangement of V kappa 4 gene segments in pre-B cell lines.Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.Relationship of the CD5 B cell to human tonsillar lymphocytes that express autoantibody-associated cross-reactive idiotypesDevelopmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia.Variable region sequences of a protective human monoclonal antibody specific for the Haemophilus influenzae type b capsular polysaccharideAnalysis of expressed and non-expressed IGK locus rearrangements in chronic lymphocytic leukemia.A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation.CD5 negative IGM rheumatoid factor B cells in B-chronic lymphocytic leukemia and benign mixed cryoglobulinemia.Autoantibody activity and V gene usage by B-cell malignancies.c-myc hypermutation in Burkitt's lymphoma.Specificity and idiotope expression of IgM produced by CD5+ and CD5- cord blood B-cell clones.Characterization of the immunoglobulin heavy chain complementarity determining region (CDR)-III sequences from human B cell precursor acute lymphoblastic leukemia cells.Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV-uninfected rhesus macaquesCD5-positive B-cell malignancies frequently express cross-reactive idiotypes associated with IgM autoantibodiesRevenge of the microbes. Superantigens of the T and B cell lineageRecombinant antibodies encoded by IGHV1-69 react with pUL32, a phosphoprotein of cytomegalovirus and B-cell superantigen.Human rheumatoid B-1a (CD5+ B) cells make somatically hypermutated high affinity IgM rheumatoid factorsOngoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells.Histologic transformation of follicular lymphoma to diffuse lymphoma represents tumor progression by a single malignant B cellEvidence for somatic selection of natural autoantibodies.Extensive and selective mutation of a rearranged VH5 gene in human B cell chronic lymphocytic leukemia.Structure of the VH and VL segments of monoreactive and polyreactive IgA autoantibodies to DNA in patients with systemic lupus erythematosusComplete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and IgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient.Uniform high frequency expression of autoantibody-associated crossreactive idiotypes in the primary B cell follicles of human fetal spleen.Distinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity.Relationship of variable region genes expressed by a human B cell lymphoma secreting pathologic anti-Pr2 erythrocyte autoantibodies.Restricted immunoglobulin variable region gene usage by normal Ly-1 (CD5+) B cells that recognize phosphatidyl choline.Lack of extensive mutations in the VH5 genes used in common B cell chronic lymphocytic leukemia.Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells.Human heavy chain variable region gene diversity, organization, and expression.From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all.The biologic significance of human natural autoimmune responses: relationship to the germline, early immune and malignant B cell variable gene repertoire.Antibody specificity of the human monoclonal immunoglobulins: the elusive target antigen.Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vkappa genes lacking somatic mutation.Immunoglobulin gene sequence analysis to further assess B-cell origin of multiple myeloma.Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.
P2860
Q30989035-B1FAC623-975E-4C9D-B9A3-7F4F855F9F2DQ33581541-8CB9D210-E99E-47CD-A4FF-9CD2D6022E7DQ33764048-FB09E81A-D19B-4A6F-9814-3F35794036C7Q33771048-709A2E8F-9D36-493F-A43D-A4A6DE7137A5Q34144917-58B31FF0-2389-48F1-A502-65F3D8E9D148Q34264984-FC5F4F0A-45EA-411A-9B6E-2A0E39F5D051Q34294671-A586B41F-D597-4211-8ACD-8FC57C6BD667Q34537160-05C33D6F-4D8A-4AED-8480-BF8E720C2B81Q34572326-519EF005-8AA3-4971-B100-5138FCBFA54DQ34579880-53BAF3AB-8A2C-4F95-84DE-832868920253Q35160039-9FBF8672-1F10-45E2-8703-4EE10CD7059AQ35168545-47039AE0-B674-4A6C-AA81-82C8639619C2Q35219287-D152BCB8-B4FB-41A7-ACF1-6A4F211C3B98Q35320991-1FBDC259-5F5E-4B49-9D75-E90FCA4D2D56Q35598751-06FE6B3D-C353-4EE3-9682-000DB9AA9C22Q35607085-7F17523E-C8C0-4861-9E44-646E359E4624Q35693333-18B9AF0B-027D-44B5-B27E-A8FB0FB8DF4BQ35811912-68E9E8D4-DDAC-42D4-AB79-22908A3EC44EQ35833626-E12CC840-BC97-451C-B902-E11CA24867AEQ35849244-A5EA501D-FC95-4FFE-891A-E73347B8E6E0Q36222893-87C14A36-E933-4F0E-BA88-4D3A95BF90B5Q36224328-6E1DCC21-E516-4CA7-84C2-F002B079E429Q36229751-D0DB4C70-E769-4B60-AA7E-A3EFB2CF4B30Q36231205-2EC068E4-4AC6-4AAF-847A-E1CD162913F5Q36231831-BF8F48FF-87F1-4B14-8860-E45958C18744Q36243271-8E2E2251-BCD7-4778-BAEF-336F82BCA5A8Q36248082-743FA8BF-047A-42A5-80DB-0F089958182DQ36350269-658A441E-E76A-406D-BB61-02DA42D67E6DQ36355658-1EDCD242-2519-436A-A91A-703102727FD7Q36356325-1BC37282-AEE7-4048-BAD9-6D878AB8D78DQ36356423-402CB66C-4757-475F-8087-D4E73E5FCA7BQ36361613-59430541-236F-4B17-8F3B-545A28934BE8Q37360579-337A77B7-36FE-441E-A8E0-3559B894740AQ37837335-3C4149BC-7F5C-4AFB-B00F-8391FE97445DQ37837345-50F625BA-9378-45A4-9078-7B8C848992FBQ37837361-000B09C0-3712-49EC-9D26-82810959E9EFQ38219282-8C0CDCF3-FBED-4004-8A6D-9195981D0622Q39791417-34244301-08DD-4F64-B430-80E07E1D05CFQ39809474-DFF3A6CF-8947-46DF-8248-3DCB80BAE58CQ39809953-A17A3DC6-0040-4E61-BFB2-2777E685A591
P2860
Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy
description
1988 nî lūn-bûn
@nan
1988 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի մարտին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Autoantibody-associated kappa ...... for etiology and immunotherapy
@ast
Autoantibody-associated kappa ...... for etiology and immunotherapy
@en
Autoantibody-associated kappa ...... for etiology and immunotherapy
@en-gb
Autoantibody-associated kappa ...... for etiology and immunotherapy
@nl
type
label
Autoantibody-associated kappa ...... for etiology and immunotherapy
@ast
Autoantibody-associated kappa ...... for etiology and immunotherapy
@en
Autoantibody-associated kappa ...... for etiology and immunotherapy
@en-gb
Autoantibody-associated kappa ...... for etiology and immunotherapy
@nl
prefLabel
Autoantibody-associated kappa ...... for etiology and immunotherapy
@ast
Autoantibody-associated kappa ...... for etiology and immunotherapy
@en
Autoantibody-associated kappa ...... for etiology and immunotherapy
@en-gb
Autoantibody-associated kappa ...... for etiology and immunotherapy
@nl
P2093
P2860
P921
P356
P1476
Autoantibody-associated kappa ...... for etiology and immunotherapy
@en
P2093
P2860
P304
P356
10.1084/JEM.167.3.840
P407
P577
1988-03-01T00:00:00Z