Immunoglobulin genes of different subgroups are interdigitated within the VK locus
about
Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapyRheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutatedHuman immunoglobulin kappa light chain genes of subgroups II and IIIConservation of sequence in recombination signal sequence spacersCloning and sequence determination of a human rheumatoid factor light-chain genePreferential rearrangement of V kappa 4 gene segments in pre-B cell lines.A novel upstream element compensates for an ineffectual octamer motif in an immunoglobulin V kappa promoter.Organization of the murine immunoglobulin VH complex in the inbred strains.Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.Defining the genetic origins of three rheumatoid synovium-derived IgG rheumatoid factors.New roles for rheumatoid factor.Structural features of transposed human VK genes and implications for the mechanism of their transpositionsHigh-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia.Analysis of genetic variation reveals human immunoglobulin VH-region gene organization.Immunoglobulin V gene expression in CD5 B-cell malignancies.Sequence analyses of three immunoglobulin G anti-virus antibodies reveal their utilization of autoantibody-related immunoglobulin Vh genes, but not V lambda genes.CD5-positive B-cell malignancies frequently express cross-reactive idiotypes associated with IgM autoantibodiesReciprocal recombination products of VK-JK joining reactions in human lymphoid cell lines.Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven responseIsolation and characterization of a light chain variable region gene for human rheumatoid factorsThe organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters.Relationship of variable region genes expressed by a human B cell lymphoma secreting pathologic anti-Pr2 erythrocyte autoantibodies.Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segmentsHuman anti-self antibodies with high specificity from phage display libraries.The endogenous Mtv-8 provirus resides within the V kappa locus.Genetic analysis of the variable region genes encoding a monospecific human natural anti-DNA antibody.Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies.Human heavy chain variable region gene diversity, organization, and expression.From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all.The biologic significance of human natural autoimmune responses: relationship to the germline, early immune and malignant B cell variable gene repertoire.Anti-DNA antibodies, autoimmunity and the immunoglobulin repertoire.Three transposed elements in the intron of a human VK immunoglobulin gene.The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA.The structural repertoire of the human V kappa domainTracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sectionsGermline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus.Transposition of human immunoglobulin V kappa genes within the same chromosome and the mechanism of their amplification.Human and mouse monoclonal antibodies to blood group A substance, which are nearly identical immunochemically, use radically different primary sequences.Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments.
P2860
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P2860
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
description
1984 nî lūn-bûn
@nan
1984 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
name
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@ast
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@en
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@en-gb
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@nl
type
label
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@ast
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@en
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@en-gb
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@nl
prefLabel
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@ast
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@en
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@en-gb
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@nl
P2860
P356
P1476
Immunoglobulin genes of different subgroups are interdigitated within the VK locus
@en
P2093
P2860
P304
P356
10.1093/NAR/12.24.9229
P407
P577
1984-12-21T00:00:00Z