Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
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Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domainRoles of lipoprotein receptors in the entry of hepatitis C virusImmune and non-immune responses to hepatitis C virus infectionHepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6Generation of Infectious Hepatitis C Virus in Immortalized Human HepatocytesViral Determinants of Resistance to Treatment in Patients with Hepatitis CAltered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studiesReduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in Hepatitis C virus repliconHepatitis C virus and ethanol alter antigen presentation in liver cellsMechanisms of action of interferon and ribavirin in chronic hepatitis C: Summary of a workshop.Impact of alcohol on hepatitis C virus replication and interferon signalingInfluence of host resistance on viral adaptation: hepatitis C virus as a case studyChIP-PED enhances the analysis of ChIP-seq and ChIP-chip dataHepcidin and the iron enigma in HCV infection.Hepatitis C virus regulates transforming growth factor beta1 production through the generation of reactive oxygen species in a nuclear factor kappaB-dependent manner.A functional genomic screen reveals novel host genes that mediate interferon-alpha's effects against hepatitis C virus.PCBP2 enhances the antiviral activity of IFN-α against HCV by stabilizing the mRNA of STAT1 and STAT2.Hepatitis C virus infection impairs IRF-7 translocation and Alpha interferon synthesis in immortalized human hepatocytesLymphotropic HCV strain can infect human primary naïve CD4+ cells and affect their proliferation and IFN-γ secretion activity.Hepatitis C virus non-structural 5A abrogates signal transducer and activator of transcription-1 nuclear translocation induced by IFN-alpha through dephosphorylation.HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NFkappaBHIV infection increases HCV-induced hepatocyte apoptosis.IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway.An overview of HCV molecular biology, replication and immune responses.Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 91HIV infection of hepatocytes results in a modest increase in hepatitis C virus expression in vitroHepatic SOCS3 expression is strongly associated with non-response to therapy and race in HCV and HCV/HIV infectionOncogenic potential of hepatitis C virus proteinsIntegrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma.EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway.Hepatitis C Virus Nonstructural Protein 5A Inhibits MG132-Induced Apoptosis of Hepatocytes in Line with NF-κB-Nuclear TranslocationType III Interferon Induces Distinct SOCS1 Expression Pattern that Contributes to Delayed but Prolonged Activation of Jak/STAT Signaling Pathway: Implications for Treatment Non-Response in HCV PatientsChanges in gene expression during pegylated interferon and ribavirin therapy of chronic hepatitis C virus distinguish responders from nonresponders to antiviral therapy.Liver-targeted antiviral peptide nanocomplexes as potential anti-HCV therapeuticsViral infection: an evolving insight into the signal transduction pathways responsible for the innate immune responseViral modulators of cullin RING ubiquitin ligases: culling the host defense.HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein responseγ-H2AX+CD8+ T lymphocytes cannot respond to IFN-α, IL-2 or IL-6 in chronic hepatitis C virus infectionProteasome activation by hepatitis C core protein is reversed by ethanol-induced oxidative stressThe role of hepatic expression of STAT1, SOCS3 and PIAS1 in the response of chronic hepatitis C patients to therapy
P2860
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P2860
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@ast
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@en
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@en-gb
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@nl
type
label
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@ast
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@en
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@en-gb
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@nl
prefLabel
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@ast
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@en
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@en-gb
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@nl
P2093
P921
P1433
P1476
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
@en
P2093
Emmett V Schmidt
Jason T Blackard
Raymond T Chung
Won Hyeok Choe
Yoichi Hiasa
Yoshitaka Kamegaya
P304
P356
10.1053/J.GASTRO.2005.02.006
P407
P577
2005-04-01T00:00:00Z